NRG4 Human

NRG4 Human

Neuregulin

Name

Description

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  • Name :

    NRG4 Human

    Description:

    Neuregulin-4 Human Recombinant

    Neuregulin 4, HRG4, Pro-neuregulin-4, membrane-bound isoform, Pro-NRG4, NRG-4.

    Product # :

    CYT-808

    Price :

    Quantity :

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  • More Info

Description

NRG4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 84 amino acids (1-61 a.a.) and having a molecular mass of 9.1kDa. NRG4 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Formulation

NRG4 protein solution (0.25mg/ml) contains 20mM Tris-HCl(pH8.0), 30% glycerol, 0.15M NaCl and 1mM DTT.

Purity

Greater than 90% as determined by SDS-PAGE.

More Info

  • Introduction

    Neuregulin-4 (NRG4) is a part of the neuregulin family that owns 1 EGF-like domain and is a low affinity ligand for the ERBB4 tyrosine kinase receptor. NRG4 links ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors.

  • Synonyms

    Neuregulin 4, HRG4, Pro-neuregulin-4, membrane-bound isoform, Pro-NRG4, NRG-4.

  • Physical Appearance

    Sterile Filtered clear solution.

  • Stability

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

  • Amino Acid Sequence

    MGSSHHHHHH SSGLVPRGSH MGSMPTDHEE PCGPSHKSFC LNGGLCYVIP TIPSPFCRCV ENYTGARCEE VFLPGSSIQT KSNL.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Nrg4 Human

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