CHMP1A Human

CHMP1A Human

Chromatin Modifying Protein

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  • Name :

    CHMP1A Human

    Description:

    Chromatin Modifying Protein 1A Human Recombinant

    Charged multivesicular body protein 1a, Chromatin-modifying protein 1a, Vacuolar protein sorting-associated protein 46-1, Vps46-1, hVps46-1, CHMP1A, CHMP1, KIAA0047, PCOLN3, PRSM1, PCH8, VPS46A.

    Product # :

    PRO-1308

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  • More Info

Description

CHMP1A Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 219 amino acids (1-196 a.a.) and having a molecular mass of 24.1kDa (Molecular size on SDS-PAGE will appear higher).CHMP1A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Formulation

CHMP1A protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 20% glycerol and 1mM DTT.

Purity

Greater than 85.0% as determined by SDS-PAGE.

More Info

  • Introduction

    Charged multivesicular body protein 1a (CHMP1A) is a member of the vacuolar sorting protein family and functions as chromatin-modifying protein. These complexes are essential for sorting endosomal articles into multivesicular bodies (MVBs), as well as vital for the formation of these bodies. The MVBs pathway mediates distribution of transmembrane proteins into the lumen of the lysosome for degradation. CHMP1 interacts with VPS4B and localizes to early endosomes.

  • Synonyms

    Charged multivesicular body protein 1a, Chromatin-modifying protein 1a, Vacuolar protein sorting-associated protein 46-1, Vps46-1, hVps46-1, CHMP1A, CHMP1, KIAA0047, PCOLN3, PRSM1, PCH8, VPS46A.

  • Physical Appearance

    Sterile Filtered colorless solution.

  • Stability

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

  • Amino Acid Sequence

    MGSSHHHHHH SSGLVPRGSH MGSMDDTLFQ LKFTAKQLEK LAKKAEKDSK AEQAKVKKAL LQKNVECARV YAENAIRKKN EGVNWLRMAS RVDAVASKVQ TAVTMKGVTK NMAQVTKALD KALSTMDLQK VSSVMDRFEQ QVQNLDVHTS VMEDSMSSAT TLTTPQEQVD SLIMQIAEEN GLEVLDQLSQ LPEGASAVGE SSVRSQEDQL SRRLAALRN.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Chmp1A Human

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