CENPU Human

CENPU Human

Centromere Protein

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  • Name :

    CENPU Human

    Description:

    Centromere Protein-U Human Recombinant

    Centromere Protein U, MLF1IP, Polo-Box-Interacting Protein 1, MLF1 Interacting Protein, Centromere Protein Of 50 KDa, Interphase Centromere Complex Protein 24, KLIP1, PBIP1, KSHV Latent Nuclear Antigen-Interacting Protein 1, MLF1-Interacting Protein, CENP50, CENPU50, KSHV Latent Nuclear Antigen Interacting Protein 1, CENP-50, CENP-U, ICEN24.

    Product # :

    PRO-1824

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  • More Info

Description

CENPU Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 295 amino acids (147-418a.a) and having a molecular mass of 33.7kDa.CENPU is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Formulation

CENPU protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.4M Urea.

Purity

Greater than 80.0% as determined by SDS-PAGE.

More Info

  • Introduction

    Centromere Protein U, also known as CENPU is a specialized chromatin domain, present throughout the cell cycle. CENPU performs as a platform on which the transient assembly of the kinetochore takes place during mitosis. CENPU plays a major role in the correct PLK1 localization to the mitotic kinetochores. A scaffold protein is responsible for the first recruitment and maintenance of the kinetochore PLK1 population until its degradation. CENPU is also implicated in transcriptional repression.

  • Synonyms

    Centromere Protein U, MLF1IP, Polo-Box-Interacting Protein 1, MLF1 Interacting Protein, Centromere Protein Of 50 KDa, Interphase Centromere Complex Protein 24, KLIP1, PBIP1, KSHV Latent Nuclear Antigen-Interacting Protein 1, MLF1-Interacting Protein, CENP50, CENPU50, KSHV Latent Nuclear Antigen Interacting Protein 1, CENP-50, CENP-U, ICEN24.

  • Physical Appearance

    Sterile Filtered clear solution.

  • Stability

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.

  • Amino Acid Sequence

    MGSSHHHHHH SSGLVPRGSH MGSTRRKVKS AEKISTQRHE VIRTTASSEL SEKPAESVTS KKTGPLSAQP SVEKENLAIE SQSKTQKKGK ISHDKRKKSR SKAIGSDTSD IVHIWCPEGM KTSDIKELNI VLPEFEKTHL EHQQRIESKV CKAAIATFYV NVKEQFIKML KESQMLTNLK RKNAKMISDI EKKRQRMIEV QDELLRLEPQ LKQLQTKYDE LKERKSSLRN AAYFLSNLKQ LYQDYSDVQA QEPNVKETYD SSSLPALLFK ARTLLGAESH LRNINHQLEK LLDQG

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Cenpu Human

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