Ubiquinol-Cytochrome C Reductase

Ubiquinol-Cytochrome C Reductase

Ubiquinol-Cytochrome C Reductase

Name

Description

Product #

Price

Quantity

Shipping Method

  • View Data Sheet

    Description:

    Ubiquinol-Cytochrome C Reductase Human Recombinant

    Cytochrome b-c1 complex subunit 8, Complex III subunit 8, Complex III subunit VIII, Ubiquinol-cytochrome c reductase complex 9.5 kDa protein, Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C, Ubiquinol-Cytochrome C Reductase, UQCRQ.

    Product # :

    ENZ-746

    Price :

    Quantity :

    Shipping Method :

    Ice Icon

    Shipped with Ice Packs

    Add To Cart

    More Info

    • description
    • source
    • formulation
    • purity
    • More Info

    Description

    UQCRQ Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 105 amino acids (1-82a.a) and having a molecular mass of 12.3kDa.UQCRQ is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

    Source

    Escherichia Coli.

    Formulation

    The UQCRQ solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea.

    Purity

    Greater than 85% as determined by SDS-PAGE.

    More Info

    • Introduction

      Ubiquinol-Cytochrome C Reductase (UQCRQ) is a small core-associated protein and a subunit of ubiquinol-cytochrome c reductase complex III that belongs to the mitochondrial respiratory chain. UQCRQ is also a ubiquinone-binding protein of low molecular mass.

    • Synonyms

      Cytochrome b-c1 complex subunit 8, Complex III subunit 8, Complex III subunit VIII, Ubiquinol-cytochrome c reductase complex 9.5 kDa protein, Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C, Ubiquinol-Cytochrome C Reductase, UQCRQ.

    • Physical Appearance

      Sterile Filtered clear solution.

    • Stability

      Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

    • Amino Acid Sequence

      MGSSHHHHHH SSGLVPRGSH MGSMGREFGN LTRMRHVISY SLSPFEQRAY PHVFTKGIPN VLRRIRESFF RVVPQFVVFY LIYTWGTEEF ERSKRKNPAA YENDK.

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

    Uqcrq Human
  • View Data Sheet

    Description:

    Ubiquinol-Cytochrome C Reductase Core Protein II Human Recombinant

    Ubiquinol-Cytochrome C Reductase Core Protein II, Ubiquinol-Cytochrome-C Reductase Complex Core Protein 2, Cytochrome B-C1 Complex Subunit 2 Mitochondrial, Complex III Subunit 2, Core Protein II, UQCR2, QCR2.

    Product # :

    PRO-1224

    Price :

    Quantity :

    Shipping Method :

    Ice Icon

    Shipped with Ice Packs

    Add To Cart

    More Info

    • description
    • source
    • formulation
    • purity
    • More Info

    Description

    UQCRC2 Human Recombinant produced in E. coli is a single polypeptide chain containing 460 amino acids (15-453) and having a molecular mass of 49.0 kDa.UQCRC2 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

    Source

    E.coli.

    Formulation

    The UQCRC2 solution contains 20mM Tris-HCl buffer (pH 8.0), 2M Urea, 0.1M NaCl and 10% glycerol.

    Purity

    Greater than 85% as determined by SDS-PAGE.

    More Info

    • Introduction

      Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) is a member of the peptidase M16 family. UQCRC2 is a component of the ubiquinol-cytochrome c reductase complex (complex III), which is a part of the mitochondrial respiratory chain. UQCRC2 is essential for the compilation of the complex.

    • Synonyms

      Ubiquinol-Cytochrome C Reductase Core Protein II, Ubiquinol-Cytochrome-C Reductase Complex Core Protein 2, Cytochrome B-C1 Complex Subunit 2 Mitochondrial, Complex III Subunit 2, Core Protein II, UQCR2, QCR2.

    • Physical Appearance

      Sterile Filtered colorless solution.

    • Stability

      Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

    • Amino Acid Sequence

      MGSSHHHHHH SSGLVPRGSH MSLKVAPKVK ATAAPAGAPP QPQDLEFTKL PNGLVIASLE NYSPVSRIGL FIKAGSRYED FSNLGTTHLL RLTSSLTTKG ASSFKITRGI EAVGGKLSVT ATRENMAYTV ECLRGDVDIL MEFLLNVTTA PEFRRWEVAD LQPQLKIDKA VAFQNPQTHV IENLHAAAYR NALANPLYCP DYRIGKVTSE ELHYFVQNHF TSARMALIGL GVSHPVLKQV AEQFLNMRGG LGLSGAKANY RGGEIREQNG DSLVHAAFVA ESAVAGSAEA NAFSVLQHVL GAGPHVKRGS NTTSHLHQAV AKATQQPFDV SAFNASYSDS GLFGIYTISQ ATAAGDVIKA AYNQVKTIAQ GNLSNTDVQA AKNKLKAGYL MSVESSECFL EEVGSQALVA GSYMPPSTVL QQIDSVANAD IINAAKKFVS GQKSMAASGN LGHTPFVDEL

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

    Uqcrc2 Human
  • View Data Sheet

    Description:

    Ubiquinol-Cytochrome C Reductase Core Protein I Human Recombinant

    D3S3191, QCR1, UQCR1, Cytochrome b-c1 complex subunit 1, mitochondrial, Complex III subunit 1, Core protein I, Ubiquinol-cytochrome-c reductase complex core protein 1.

    Product # :

    PRO-1894

    Price :

    Quantity :

    Shipping Method :

    Ice Icon

    Shipped with Ice Packs

    Add To Cart

    More Info

    • description
    • source
    • formulation
    • purity
    • More Info

    Description

    UQCRC1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 471 amino acids (35-480 a.a) and having a molecular mass of 51.8kDa.UQCRC1 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

    Source

    Escherichia Coli.

    Formulation

    UQCRC1protein solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M UREA and 10% glycerol.

    Purity

    Greater than 85.0% as determined by SDS-PAGE.

    More Info

    • Introduction

      Ubiquinol-Cytochrome C Reductase Core Protein I (UQCRC1) is a member of the peptidase M16 family,UQCRC1/QCR1 subfamily. UQCRC1 is a part of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is component of the mitochondrial respiratory chain. UQCRC1 can mediate formation of the complex between cytochromes c and c1.

    • Synonyms

      D3S3191, QCR1, UQCR1, Cytochrome b-c1 complex subunit 1, mitochondrial, Complex III subunit 1, Core protein I, Ubiquinol-cytochrome-c reductase complex core protein 1.

    • Physical Appearance

      Sterile Filtered clear solution.

    • Stability

      Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

    • Amino Acid Sequence

      MGSSHHHHHH SSGLVPRGSH MGSEFTATFA QALQFVPETQ VSLLDNGLRV ASEQSSQPTC TVGVWIDVGS RFETEKNNGA GYFLEHLAFK GTKNRPGSAL EKEVESMGAH LNAYSTREHT AYYIKALSKD LPKAVELLGD IVQNCSLEDS QIEKERDVIL REMQENDASM RDVVFNYLHA TAFQGTPLAQ AVEGPSENVR KLSRADLTEY LSTHYKAPRM VLAAAGGVEH QQLLDLAQKH LGGIPWTYAE DAVPTLTPCR FTGSEIRHRD DALPFAHVAI AVEGPGWASP DNVALQVANA IIGHYDCTYG GGVHLSSPLA SGAVANKLCQ SFQTFSICYA ETGLLGAHFV CDRMKIDDMM FVLQGQWMRL CTSATESEVA RGKNILRNAL VSHLDGTTPV CEDIGRSLLT YGRRIPLAEW ESRIAEVDAS VVREICSKYI YDQCPAVAGY GPIEQLPDYN RIRSGMFWLR F.

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

    Uqcrc1 Human

About Ubiquinol-Cytochrome C Reductase:

Ubiquinol-Cytochrome C Reductase, also known as UQCRC and sometimes called Complex III is the usual third element in the Electron Transport Chain, which plays a significant role in the biochemical production of (oxidative phosphorylation) ATP. This element is a multiple subunit transmembrane protein that is encoded by mitochondrial as well as nuclear genomes. This protein can be found in all eukaryotes, the internal membranes of almost all eubacteria, and the mitochondria of all animals.

UQCRC Structure
The number of subunits found in this element is small, like three polypeptides likened to the other key proton-pumping sub elements. In higher animals, this number can increase up to eleven subunits.
Three subunits have prosthetic assemblies, which are the Cytochrome b subunit with binary b-type hemes, Cytochrome c subunit with a single c-type heme, and Rieske iron-sulfur protein subunit that has two iron, and two sulfur (2Fe.2S).
The Complex III is located in the center of the respiratory chain tolerant electrons from the Complexes I, II, flavoproteins that transfer electrons and other flavoproteins through Ubiquinol.

Ubiquinol-Cytochrome C Reductase Interaction
There are 98 protein-protein interactions in UQCRC, 90 of which are co-complex interactions. Mapk3, QCR1, CAC1A, STOM, CACNA1A, and HLA-B have all been found to i9netact with UQCRC.

UQCRC Function
The Ubiquinol – Cytochrome C Reductase plays a major role as an energy transducing and energy transference enzyme found in the inner mitochondrial membrane of oxygen-using eukaryotic cells; this protein takes part in cell respiration.
The protein coded by this gene is located in the mitochondrion, where it is part of the UQCRC. It is also part of the mitochondrial respiratory chain. The core protein UQCRC is needed for the collection and stabilization of the complex.