TLR2 Antibody

TLR2 Antibody

Monoclonal Antibodies

Name

Description

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Quantity

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  • Name :

    TLR2 Antibody

    Description:

    Toll-like receptor 2, Mouse Anti Human

    Toll-like receptor 2, Toll/interleukin-1 receptor-like protein 4, CD282, TLR2, TIL4.

    Product # :

    ANT-408

    Price :

    Quantity :

    Shipping Method :

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  • formulation
  • More Info

Formulation

1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.

More Info

  • Introduction

    TLR2 belongs to the Toll-like receptor (TLR) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) which are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

  • Synonyms

    Toll-like receptor 2, Toll/interleukin-1 receptor-like protein 4, CD282, TLR2, TIL4.

  • Physical Appearance

    Sterile filtered colorless solution.

  • Immunogen

    Anti-human TLR2 mAb, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TLR2 amino acids 221-384 purified from E. coli.

  • Ig Subclass

    Mouse IgG1 heavy chain and κ light chain.

  • Clone

    P1F10AT.

  • Applications

    TLR2 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1,000. Recommended starting dilution is 1:500.

  • Type

    Mouse Anti Human Monoclonal.

  • Storage Procedures

    For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

  • Purification Method

    TLR2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Tlr2 Antibody

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