TARS Human, Sf9

TARS Human, Sf9

Enzymes

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  • Name :

    TARS Human, Sf9

    Description:

    Threonyl-tRNA Synthetase Human Recombinant, Sf9

    Threonyl-tRNA synthetase cytoplasmic, EC 6.1.1.3, Threonine-tRNA ligase, ThrRS, MGC9344, PL-7, TARS.

    Product # :

    ENZ-304

    Price :

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  • formulation
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  • More Info

Description

PL-7 Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a molecular mass of 85kDa.PL-7 is expressed with a -6xHis tag and purified by proprietary chromatographic techniques.

Source

Sf9 insect cells.

Formulation

PL-7 is supplied in 20mM HEPES buffer pH-8, 200mM NaCl, and 20% glycerol.

Purity

Greater than 90% as determined by SDS-PAGE.

More Info

  • Introduction

    Threonyl-tRNA Synthetase is a member of the aminoacyl-tRNA synthetase family, key enzymes of protein biosynthesis which charge tRNA molecules with the respective amino acids. This 83 kDa protein is an autoantigen recognized by PL-7 antibodies which occur in a subset of patients with polymyositis and dermatomyositis. Preliminary data suggest that PL-7 antibodies (similar to Jo-1 antibodies) indicate an increased risk for lung involvement, but this needs to be confirmed for a larger number of cases.

  • Synonyms

    Threonyl-tRNA synthetase cytoplasmic, EC 6.1.1.3, Threonine-tRNA ligase, ThrRS, MGC9344, PL-7, TARS.

  • Physical Appearance

    Sterile Filtered clear solution.

  • Stability

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.

  • Immunological Functions

    1. Binds IgG-type human auto-antibodies.2. Standard ELISA test (checker-board analysis of positive/negative sera panels immuno-dot test).

  • coating concentration

    0.3-0.8 µg/ml (depending on the type of ELISA plate and coating buffer). Suitable for labeling of functional groups.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Threonyl Trna Synthetase Human

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