TARDBP Antibody

TARDBP Antibody

Monoclonal Antibodies

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Description

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  • Name :

    TARDBP Antibody

    Description:

    TAR DNA-binding protein 43, Mouse Anti Human

    TAR DNA-binding protein 43, TDP-43, TARDBP, TDP43, ALS10.

    Product # :

    ANT-420

    Price :

    Quantity :

    Shipping Method :

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  • formulation
  • More Info

Formulation

1mg/ml containing PBS, pH-7.4, 10% Glycerol & 0.02% Sodium Azide.

More Info

  • Introduction

    HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome which produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TARDBP is a transcriptional repressor which binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, TARDBP regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.

  • Synonyms

    TAR DNA-binding protein 43, TDP-43, TARDBP, TDP43, ALS10.

  • Physical Appearance

    Sterile filtered colorless solution.

  • Immunogen

    Anti-human TARDBP mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TARDBP amino acids 1-260 purified from E. coli.

  • Ig Subclass

    Mouse IgG1 heavy chain and κ light chain.

  • Clone

    Pk1B8AT.

  • Applications

    TARDBP antibody has been tested by ELISA, Western blot, FACS and immunohistochemistry analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

  • Type

    Mouse Anti Human Monoclonal.

  • Storage Procedures

    For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

  • Purification Method

    TARDBP antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Tardbp Antibody

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