SIRPB1 Human

SIRPB1 Human

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  • Name :

    SIRPB1 Human

    Description:

    Recombinant Human Signal Regulatory Protein Beta 1

    SIRPB1, CD172b, SIRP-BETA-1, SIRP-Beta-1 Isoform 3, CD172b Antigen, CD172b.

    Product # :

    PRO-2545

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  • More Info

Description

SIRPB1produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (30-371 a.a.) and fused to a 6 aa His Tag at C-terminus containing a total of 348 amino acids and having a molecular mass of 38.0kDa. SIRPB1shows multiple bands between 40-57kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques.

Source

Sf9, Baculovirus cells.

Formulation

SIRPB1protein solution (0.25mg/ml) contains Phosphate Buffered Saline (pH 7.4) & 10% glycerol.

Purity

Greater than 90.0% as determined by SDS-PAGE.

More Info

  • Introduction

    Signal-regulatory protein beta-1 isoform 1 or SIRPB1, is an immunoglobulin-like cell surface receptor which is a part of the SIRP superfamily. SIRPB1 is a cell membrane receptor that takes part in the negative regulation of tyrosine kinase-coupled signaling pathway. SIRPB1 is engaged in the activation of tyrosine kinase SYK, SIRP alpha molecules (activates SHP-1 and SHP-2 protein tyrosine phosphatases), etc.

  • Synonyms

    SIRPB1, CD172b, SIRP-BETA-1, SIRP-Beta-1 Isoform 3, CD172b Antigen, CD172b.

  • Physical Appearance

    Sterile Filtered colorless solution.

  • Stability

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

  • Amino Acid Sequence

    EDELQVIQPE KSVSVAAGES ATLRCAMTSL IPVGPIMWFR GAGAGRELIY NQKEGHFPRV TTVSELTKRN NLDFSISISN ITPADAGTYY CVKFRKGSPD DVEFKSGAGT ELSVRAKPSA PVVSGPAVRA TPEHTVSFTC ESHGFSPRDI TLKWFKNGNE LSDFQTNVDP AGDSVSYSIH STARVVLTRG DVHSQVICEI AHITLQGDPL RGTANLSEAI RVPPTLEVTQ QPMRAENQAN VTCQVSNFYP RGLQLTWLEN GNVSRTETAS TLIENKDGTY NWMSWLLVNT CAHRDDVVLT CQVEHDGQQA VSKSYALEIS AHQKEHGSDI THEAALAPTA PLHHHHHH.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Sirpb1 Human

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