Selank, also known as TP-7, is a synthetic peptide that has garnered significant attention in the scientific community due to its potential anxiolytic, neuroprotective, and nootropic effects. This heptapeptide, derived from the naturally occurring human tetrapeptide Tuftsin, has been shown to possess a wide range of biological activities, including enhancing memory, reducing anxiety, and potentially mitigating the effects of neurodegenerative diseases.
Selank's primary mechanism of action involves its interaction with the GABAergic system, the body's main inhibitory neurotransmitter system. By modulating the activity of GABA receptors, Selank can exert a calming effect on the brain, reducing anxiety and enhancing cognitive function. Studies by Semenova et al. (2014) have demonstrated that Selank can enhance memory and learning in rats, suggesting potential applications in cognitive enhancement and the treatment of cognitive disorders.
In addition to its anxiolytic and nootropic effects, Selank has been shown to possess neuroprotective properties. Research by Ershov et al. (2016) found that Selank could protect neurons from oxidative stress, suggesting potential applications in the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's disease.
Given its anxiolytic, nootropic, and neuroprotective effects, Selank has been proposed as a potential therapeutic agent for a variety of conditions, including anxiety disorders, cognitive disorders, and neurodegenerative diseases. For instance, a study by Medvedev et al. (2017) found that Selank could improve symptoms in patients with generalized anxiety disorder, indicating its potential as a therapeutic agent in the treatment of anxiety disorders.
While research on Selank is promising, it is important to note that most studies have been conducted in animals or in vitro. More research is needed to fully understand the potential effects and applications of Selank in humans. However, the existing body of research suggests that Selank could be a promising tool in the treatment of anxiety disorders, cognitive disorders, and neurodegenerative diseases.
What is the molecular weight/Mw of SELANK Protein?
SELANK Protein has a total Mw of 0.751kDa.
What is the Purity of SELANK Protein?
SELANK Protein is >97% pure as determined by SDS-PAGE.
What is the Biological Activity of SELANK Protein?
The biological functionality of SELANK Protein will be determined in the future.
What is the amino acid sequence of SELANK Protein?
H-Thr-Lys-Pro-Arg-Pro-Gly-Pro-OH.
What applications can SELANK Protein be used in?
SELANK Protein can probably be used in western blot, ELISA and Lateral Flow.
What is the endotoxin level for SELANK Protein?
The endotoxin level is minimal, SELANK Protein was purified using conventional chromatography techniques.
Who supplies SELANK that is in stock and available to order?
ProSpec has the protein in stock and available for immediate delivery.
Where can I order bulk mg quantities of SELANK?
ProSpec supplies bulk mg quantities at affordable prices that meets research and academic budgets.