PON1 Human (68-124)

PON1 Human (68-124)

Enzymes

Name

Description

Product #

Price

Quantity

Shipping Method

  • Name :

    PON1 Human (68-124)

    Description:

    Paraoxonase-1 (68-124) Human Recombinant

    Serum paraoxonase, arylesterase 1, EC 3.1.1.2, EC 3.1.8.1, PON 1.

    Product # :

    ENZ-1197

    Price :

    Quantity :

    Shipping Method :

    Room Temp Icon

    Shipped at Room temp

    Add :

  • description
  • source
  • formulation
  • purity
  • More Info

Description

The PON1 Human is created as a recombinant protein with a 4kda N-terminal fusion of His Tag. The PON1 His-Tagged Fusion Protein, produced in E. coli, is a 12kDa protein containing 57 amino acid residues of the PON1 Human, 68-124 amino acids.

Source

Escherichia Coli.

Formulation

Each mg was lyophilized with 1xPBS, 0.4% SDS and 4mM DTT.

Purity

Greater than 90% as determined by SDS-PAGE.

More Info

  • Synonyms

    Serum paraoxonase, arylesterase 1, EC 3.1.1.2, EC 3.1.8.1, PON 1.

  • Physical Appearance

    Filtered White lyophilized (freeze-dried) powder.

  • Stability

    Store lyophilized PON1 at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

  • Solubility

    It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile!

    Please filter the product by an appropriate sterile filter before using it on cell culture.

  • Background

    Paraoxonase 1 also known as PON1takes part in the detoxification of organophosphate insecticides such as parathion.

    PON1 is related to high-density lipoprotein (HDL) in the plasma and takes an important part in lipid metabolism and antioxidant defense.

    PON1 was first known for its ability to hydrolyze organophosphates and protect against oxidative stress.

    PON1 reduces oxidative stress by preventing the oxidation of lipids in LDL particles, which is extremely important in mitigating atherosclerosis and other cardiovascular diseases.

    PON1 has an anti-inflammatory effects which help reduce inflammatory markers in different disease states.

    PON1 takes part in cholesterol metabolism, influencing the stability and formation of HDL particles, which are vital for lipid transport and reverse cholesterol efflux.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Pon1 Protein

You may also like