POLR1C Human

POLR1C Human

Polymerase (RNA) (DNA directed) Polypeptide

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  • Name :

    POLR1C Human

    Description:

    Polymerase (RNA) I (DNA directed) Polypeptide C Human Recombinant

    DNA-directed RNA polymerases I and III subunit RPAC1, POLR1C, POLR1E, RPC40, Polymerase (RNA) I (DNA directed) Polypeptide C, RPA40, RPA39, DNA-directed RNA polymerases I and III 40 kDa polypeptide, RNA polymerases I and III subunit AC1, AC40, DNA-directed RNA polymerase I subunit C, RP3-337H4.4, RPA5, RPAC1, TCS3.

    Product # :

    PRO-2018

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  • More Info

Description

POLR1C Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 369 amino acids (1-346 a.a.) and having a molecular mass of 41.6kDa.POLR1C is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Formulation

POLR1C protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT.

Purity

Greater than 80.0% as determined by SDS-PAGE.

More Info

  • Introduction

    Polymerase (RNA) I (DNA directed) Polypeptide C (POLR1C) is a subunit of both RNA polymerase I and RNA polymerase III complexes whose defects are related with Collins syndrome. POLR1C is a protein-coding gene and is part of the Pol core element

  • Synonyms

    DNA-directed RNA polymerases I and III subunit RPAC1, POLR1C, POLR1E, RPC40, Polymerase (RNA) I (DNA directed) Polypeptide C, RPA40, RPA39, DNA-directed RNA polymerases I and III 40 kDa polypeptide, RNA polymerases I and III subunit AC1, AC40, DNA-directed RNA polymerase I subunit C, RP3-337H4.4, RPA5, RPAC1, TCS3.

  • Physical Appearance

    Sterile Filtered colorless solution.

  • Stability

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

  • Amino Acid Sequence

    MGSSHHHHHH SSGLVPRGSH MGSMAASQAV EEMRSRVVLG EFGVRNVHTT DFPGNYSGYD DAWDQDRFEK NFRVDVVHMD ENSLEFDMVG IDAAIANAFR RILLAEVPTM AVEKVLVYNN TSIVQDEILA HRLGLIPIHA DPRLFEYRNQ GDEEGTEIDT LQFRLQVRCT RNPHAAKDSS DPNELYVNHK VYTRHMTWIP LGNQADLFPE GTIRPVHDDI LIAQLRPGQE IDLLMHCVKG IGKDHAKFSP VATASYRLLP DITLLEPVEG EAAEELSRCF SPGVIEVQEV QGKKVARVAN PRLDTFSREI FRNEKLKKVV RLARVRDHYI FSVESTGVLP PDVLVSEAIK VLMGKCRRFL DELDAVQMD.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Polr1C Human

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