Ornipressin

Ornipressin

Hormones

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  • Name :

    Ornipressin

    Description:

    Ornipressin

    Product # :

    HOR-036

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    Shipped at Room temp

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Description

Ornipressin Synthetic is a single, non-glycosylated polypeptide chain containing 9 amino acids, having a molecular mass of 1042.19 Dalton and a Molecular formula of C45H63N13O12 S2.

Formulation

The protein was lyophilized with no additives.

Purity

Greater than 97.0% as determined by analysis by RP-HPLC.

More Info

  • Physical Appearance

    Sterile Filtered White lyophilized (freeze-dried) powder.

  • Stability

    Lyophilized Ornipressin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Ornipressin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

  • Solubility

    It is recommended to reconstitute the lyophilized Ornipressin in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

  • Amino Acid Sequence

    H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Orn-Gly-NH2.

  • Background

    Ornipressin, a naturally occurring non-mammalian vasopressin analogue, has been recognized for its role in vasoconstriction and antidiuresis, making it an invaluable agent in certain clinical settings (Holmes et al., 2003). This paper aims to comprehensively review ornipressin's biochemical properties, its clinical applications, and potential future directions for therapeutic use.

    Ornipressin is characterized by its strong vasopressin V1 receptor agonist activity, resulting in intense vasoconstriction. It also exhibits antidiuretic properties through the activation of V2 receptors in the renal collecting ducts, albeit to a lesser extent compared to vasopressin (Evans & Davidson, 1964).

    Clinical applications of ornipressin are mainly driven by its potent vasoconstrictor activity. It has shown promise in managing esophageal variceal bleeding, where its vasoconstrictive properties help achieve hemostasis (Bosch et al., 2004).

    Furthermore, it has been used as a rescue therapy in vasodilatory shock, where traditional vasoconstrictors may have limited effect (Morelli et al., 2005).
    As our understanding of ornipressin continues to expand, future research is directed toward fine-tuning its application in various clinical scenarios and exploring potential new therapeutic roles. Current research is investigating the possible neuroprotective role of ornipressin in conditions such as cerebral ischemia (Uchida et al., 2010).

    Ornipressin, with its robust vasoconstrictor and antidiuretic properties, plays a crucial role in managing certain clinical situations. As we continue to explore this intriguing compound, its therapeutic potential appears to be far-reaching, warranting continued research in this field.

    What is the molecular weight/Mw of ORNIPRESSIN Protein?
    ORNIPRESSIN Protein has a total Mw of 1.042 kDa.

    What is the Purity of ORNIPRESSIN Protein?
    ORNIPRESSIN Protein is >97% pure as determined by SDS-PAGE.

    What is the Biological Activity of ORNIPRESSIN Protein?
    The biological functionality of ORNIPRESSIN Protein will be determined in the future.

    What is the amino acid sequence of ORNIPRESSIN Protein?
    H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Orn-Gly-NH2.

    What applications can ORNIPRESSIN Protein be used in?
    ORNIPRESSIN Protein can probably be used in western blot, ELISA and Lateral Flow.

    What is the endotoxin level for ORNIPRESSIN Protein?
    The endotoxin level is minimal, ORNIPRESSIN Protein was purified using conventional chromatography techniques.

    Who supplies ORNIPRESSIN that is in stock and available to order?
    ProSpec has the protein in stock and available for immediate delivery.

    Where can I order bulk mg quantities of ORNIPRESSIN?
    ProSpec supplies bulk mg quantities at affordable prices that meets research and academic budgets.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Ornipressin

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