OBFC1 Human

OBFC1 Human

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  • Name :

    OBFC1 Human

    Description:

    Oligonucleotide Binding Fold Containing 1 Human Recombinant

    AAF-44, RPA-32, STN1, CST complex subunit STN1, Suppressor of cdc thirteen homolog, Oligonucleotide/oligosaccharide-binding fold-containing protein 1, OBFC1.

    Product # :

    PRO-028

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  • More Info

Description

OBFC1 Human Recombinant produced in E. coli is. a single polypeptide chain containing 391 amino acids (1-368) and having a molecular mass of 44.5kDa. OBFC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Formulation

The OBFC1 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT.

Purity

Greater than 85% as determined by SDS-PAGE.

More Info

  • Introduction

    Oligonucleotide Binding Fold Containing 1 (OBFC1) is a part of the CST complex, a complex which binds to single-stranded DNA and is essential to defend telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent way, whereas isolated subunits bind DNA with low affinity by themselves. The role of the CST complex is less specific in DNA metabolism at non-telomeric sites.

  • Synonyms

    AAF-44, RPA-32, STN1, CST complex subunit STN1, Suppressor of cdc thirteen homolog, Oligonucleotide/oligosaccharide-binding fold-containing protein 1, OBFC1.

  • Physical Appearance

    Sterile Filtered clear solution.

  • Stability

    Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

  • Amino Acid Sequence

    MGSSHHHHHH SSGLVPRGSH MGSMQPGSSR CEEETPSLLW GLDPVFLAFA KLYIRDILDM KESRQVPGVF LYNGHPIKQV DVLGTVIGVR ERDAFYSYGV DDSTGVINCI CWKKLNTESV SAAPSAAREL SLTSQLKKLQ ETIEQKTKIE IGDTIRVRGS IRTYREEREI HATAYYKVDD PVWNIQIARM LELPTIYRKV YDQPFHSSAL EKEEALSNPG ALDLPSLTSL LSEKAKEFLM ENRVQSFYQQ ELEMVESLLS LANQPVIHSA CSDQVNFKKD TTSKAIHSIF KNAIQLLQEK GLVFQKDDGF DNLYYVTRED KDLHRKIHRI IQQDCQKPNH MEKGCHFLHI LACARLSIRP GLSEAVLQQV LELLEDQSDI VSTMEHYYTA F.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Obfc1 Human

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