NANOG Antibody

NANOG Antibody

Monoclonal Antibodies

Name

Description

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  • Name :

    NANOG Antibody

    Description:

    Homeobox Protein NANOG, Mouse Anti Human

    NANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog, hNanog.

    Product # :

    ANT-422

    Price :

    Quantity :

    Shipping Method :

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    Shipped with Ice Packs

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  • formulation
  • More Info

Formulation

1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.

More Info

  • Introduction

    NANOG is a multidomain homeobox transcription factor which functions to maintain the undifferentiated state of pluripotent stem cells. NANOG expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53.

  • Synonyms

    NANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog, hNanog.

  • Immunogen

    Anti-human NANOG mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human NANOG amino acids 1-154 purified from E. coli.

  • Ig Subclass

    Mouse IgG2a heavy chain and κ light chain.

  • Clone

    P5A10AT.

  • Applications

    NANOG antibody has been tested by ELISA, Western blot and immunohistochemistry analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot is 1:500~1:1,000 and immunohistochemistry analysis is 1:50~100. Recommended starting dilution for Western blot is 1:500 and Immunohistochemistry is 1:50.

  • Type

    Mouse Anti Human Monoclonal.

  • Storage Procedures

    For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

  • Purification Method

    NANOG antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Nanog Antibody

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