LY6G Antibody, Biotin

LY6G Antibody, Biotin

Monoclonal Antibodies

Name

Description

Product #

Price

Quantity

Shipping Method

  • Name :

    LY6G Antibody, Biotin

    Description:

    LY6G, Rat Anti Mouse Antibody, Biotin

    Lymphocyte antigen 6G, Ly-6G, Ly-6G.1, Ly6g, Gr1, Gr-1.

    Product # :

    ANT-074

    Price :

    Quantity :

    Shipping Method :

    Room Temp Icon

    Shipped at Room temp

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  • formulation
  • More Info

Formulation

1mg/ml in PBS (after reconstitution).

More Info

  • Introduction

    Myeloid differentiation antigen Gr1 (Ly6G) is a GPI-anchored protein, which is briefly expressed on monocytes in the bone marrow. The level of the Ly6G expression in the bone marrow completely correlates with granulocyte differentiation and maturation. Ly6G ligation on murine neutrophils inhibits neutrophil recruitment, thus providing the first evidence of a function for the Ly6G molecule. Ly6G is seen primarily on neutrophils, also in a subgroup of eosinophils, differentiating pre-monocytes and plasmacytoid dendritic cells.

  • Synonyms

    Lymphocyte antigen 6G, Ly-6G, Ly-6G.1, Ly6g, Gr1, Gr-1.

  • Solubility

    Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

  • Immunogen

    Ly-6G-transfected cell line.

  • Ig Subclass

    Rat IgG2a.

  • Clone

    YRmLy-6G.

  • Applications

    Flow cytometry, immunohistochemistry, cell depletion.
    This antibody recognizes only Ly-6G which is expressed on most myeloid cells in the bone marrow and all peripheral granulocytes. For flow cytometry, use 10 µl/106 cells. Exact titer for cell depletion in vivo (cytotoxicity) should be determined by the investigator.

  • Shipping Conditions

    Antibody is shipped lyophilized at ambient temperature.

  • Available Conjugates

    This antibody is also available unconjugated and conjugated to FITC.

  • Type

    Rat Anti Mouse Monoclonal.

  • Storage Procedures

    In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

  • Purification Method

    Protein A column.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Ly6G Antibody Biotin

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