HIV-2 Protease

HIV-2 Protease

HIV

Name

Description

Product #

Price

Quantity

Shipping Method

  • Name :

    HIV-2 Protease

    Description:

    HIV-2 Protease Recombinant

    Product # :

    HIV-002

    Price :

    Quantity :

    Shipping Method :

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  • description
  • source
  • formulation
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Description

HIV-2 protease is an active homodimer having a molecular mass of 10.7kDa.

Source

Escherichia Coli.

Formulation

The HIV-2 Protease solution (0.25mg/1ml) is formulated in 20mM Tris pH7.0, 20mM MES, 200mM NaCl, 1mM EDT, 0.5mM DTT, 0.05% PEG 8000and 10% glycerol.

More Info

  • Introduction

    HIV-2 protease is very significant in the life cycle of the HIV virus. It is expressed in the infected cells as a part of Gag-Pol polyprotein from which it is auto-catalytycaly released after formation of an immature viral particle. The enzyme subsequently cleaves the other parts of viral polyproteins resulting in the maturation of the virus. In HIV-infected patients the enzyme is subjected to intensive mutagenesis and mutants resistant to applied medicines are produced as a result of the selection pressure.

  • Physical Appearance

    Sterile filtered colorless clear solution.

  • Stability

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.Please avoid freeze thaw cycles.

  • Storage Buffer

    20mM HEPES, pH7.0 and 10% Glycerol.

  • Kinetic parameters

    Km=740µM, Kcat = 30s-1, Kcat/Km=4.1mM-1s-1 with peptide substrate ATLNFPISPW.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Hiv 2 Protease

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