HDGF Human

HDGF Human

Growth Factors

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  • Name :

    HDGF Human

    Description:

    Hepatoma-Derived Growth Factor Human Recombinant

    High-mobility group protein 1-like 2, HMG1L2, HMG-1L2, Hepatoma-derived growth factor, HDGF, FLJ96580, DKFZp686J1764.

    Product # :

    CYT-681

    Price :

    Quantity :

    Shipping Method :

    Ice Icon

    Shipped with Ice Packs

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  • description
  • source
  • formulation
  • purity
  • More Info

Description

The HDGF Human recombinant protein is a single, non-glycosylated polypeptide chain produced in E. coli, having a molecular weight of 11.5kDa and containing 100 amino acids.The HDGF is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Formulation

The HDGF protein solution (1mg/ml) is formulated in 20mM Tris-HCl pH-7.5, 1mM DTT, 10% glycerol and 1mM EDTA.

Purity

Greater than 95% as determined by SDS-PAGE.

More Info

  • Introduction

    HDGF is a member of the hepatoma-derived growth factor family. HDGF plays a role as a secreted mitogen from the human hepatoma cell line Huh-7. HDGF is a nuclear targeted vascular smooth muscle cell mitogen as well as a heparin-binding protein that is greatly expressed in tumor cells where it stimulates proliferation. HDGF takes part in organ development and lung remodeling after injury by promoting proliferation of lung epithelial cells. HDGF plays a role in the carcinogenesis of gastric epithelial cells through promotion of cell proliferation by Erk1/2 activation. HDGF is linked with tumorigenesis and the growth of cancer. HDGF is a self-regulating factor connected with the prognosis of liver cancer, non-small cell lung cancer and pancreatic cancer. HDGF has proliferative, angiogenic, and neurotrophic activity. HDGF is a distinctive nuclear targeting growth factor that is vastly expressed in HCC cells and is a prognostic factor for HCC.

  • Synonyms

    High-mobility group protein 1-like 2, HMG1L2, HMG-1L2, Hepatoma-derived growth factor, HDGF, FLJ96580, DKFZp686J1764.

  • Physical Appearance

    Sterile Filtered clear solution.

  • Stability

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

  • Amino Acid Sequence

    MSRSNRQKEY KCGDLVFAKM KGYPHWPARI DEMPEAAVKS TANKYQVFFF GTHETAFLGP KDLFPYEESK EKFGKPNKRK GFSEGLWEIE NNPTVKASGY.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Hdgf Human

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Frequently asked questions

1. Which company offers Recombinant Growth Factors at competitive prices?

ProSpec offers vast array of Growth Factors such as EGF| IGF1 | Leptin| VEGF and much more at affordable descent prices to meet academic budgets
ProSpec provides High Purity Growth Factors for 30 years, purity exhibits 95% and more as visualized by SDS-PAGE gel.
Growth Factors are in stock for immediate delivery via FedEx which enables scientists and researchers to perform immediate experiments.
Growth Factors are shipped globally using ProSpec’s custom tailored Styrofoam insulated box and premium ice packs that ensure maximum protein stability during transit to your laboratory.

2. Where can i find biologically active Growth Factors?

ProSpec offers biologically functional Growth Factors such as Prolactin | Erythropoietin | PDGF-BB which are rigorously tested in-vitro to provide researchers world wide BioActive Growth Factors.