HCV NS4 (1916-1947 a.a.)

HCV NS4 (1916-1947 a.a.)

Hepatitis C

Name

Description

Product #

Price

Quantity

Shipping Method

  • Name :

    HCV NS4 (1916-1947 a.a.)

    Description:

    Hepatitis C Virus NS4 (1916-1947 a.a.) Recombinant

    Product # :

    HCV-202

    Price :

    Quantity :

    Shipping Method :

    Ice Icon

    Shipped with Ice Packs

    Add :

  • description
  • formulation
  • purity
  • More Info

Description

E.coli derived 30 kDa recombinant protein. Artificial mosaic polypeptide composite constructed from diagnostically relevant antigenic regions derived from the NS4 region.

Formulation

1.5M urea, 25mM Tris-HCl pH-8, 0.2% Triton-X & 50% Glycerol.

Purity

HCV NS4 protein is >95% pure as determined by 10% PAGE (coomassie staining).

More Info

  • Introduction

    HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae.
    HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to IFN-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to IFN-based treatment than are the other genotypes (2, 3, 5 and 6).

  • Stability

    HCV NS4 although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.

  • Applications

    HCV NS4 antigen is suitable for ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems.

  • Specificity

    Immunoreactive with sera of HCV-infected individuals.

  • Purification Method

    HCV NS4 protein was purified by proprietary chromatographic technique.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Hcv Ns4

You may also like