GYPA Antibody

GYPA Antibody

Monoclonal Antibodies

Name

Description

Product #

Price

Quantity

Shipping Method

  • Name :

    GYPA Antibody

    Description:

    Glycophorin A (type M & type N), Mouse Anti Human Antibody

    Glycophorin-A, MN sialoglycoprotein, PAS-2, Sialoglycoprotein alpha, CD235a, GYPA, GPA, MN, MNS, GPSAT, GPErik, HGpMiV, HGpMiXI, HGpSta(C).

    Product # :

    ANT-231

    Price :

    Quantity :

    Shipping Method :

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    Shipped at Room temp

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  • formulation
  • More Info

Formulation

1mg/ml in PBS (after reconstitution).

More Info

  • Introduction

    Glycophorins A & B (GYPA &GYPB) are the main sialoglycoproteins of the human erythrocyte membrane which carry the antigenic determinants for the MN and Ss blood groups. Along with the M or N and S or s antigens which normally occur in all populations, approximately 40 related variant phenotypes were identified. These variants comprise all the variants of the Miltenberger complex and some isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. GYPA is significant for the function of SLC4A1 and is necessary for high activity of SLC4A1. GYPA is involved in translocation of SLC4A1 to the plasma membrane. GYPA is also a receptor for: the influenza virus, Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans and is also a receptor for Hepatitis A virus (HAV).

  • Synonyms

    Glycophorin-A, MN sialoglycoprotein, PAS-2, Sialoglycoprotein alpha, CD235a, GYPA, GPA, MN, MNS, GPSAT, GPErik, HGpMiV, HGpMiXI, HGpSta(C).

  • Solubility

    Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

  • Immunogen

    r.Human GlycophorinA.

  • Ig Subclass

    Mouse IgG1.

  • Clone

    NYRhGlycophorinA.

  • Applications

    Western Blot, imunohistochemistry, flow cytometry. For WB use 1µg/ml of antibody. For flow cytometry use 5-10 µl per one million cells.

  • Titer

    By direct ELISA, 1:10,000 dilution will yield 0.5 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories).

  • Shipping Conditions

    Antibody is shipped lyophilized at ambient temperature.

  • Type

    Mouse Anti Human Monoclonal Antibody.

  • Storage Procedures

    In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

  • Purification Method

    Protein A column.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Gypa Antibody

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