GNB2L1 Human

GNB2L1 Human

Guanine Nucleotide Binding Protein

Name

Description

Product #

Price

Quantity

Shipping Method

  • Name :

    GNB2L1 Human

    Description:

    Guanine Nucleotide Binding Protein beta polypeptide 2-like 1 Human Recombinant

    Guanine nucleotide binding protein (G protein) beta polypeptide 2-like 1, RACK1, Receptor for Activated C Kinase 1, Gnb2-rs1, H12.3, Cell proliferation-inducing gene 21 protein, Guanine nucleotide-binding protein subunit beta-like protein 12.3, Human lung cancer oncogene 7 protein, Receptor of activated protein kinase C 1, HLC-7, PIG21, proliferation-inducing gene 21, protein homologous to chicken B complex protein guanine nucleotide binding.

    Product # :

    PRO-1023

    Price :

    Quantity :

    Shipping Method :

    Ice Icon

    Shipped with Ice Packs

    Add :

  • description
  • source
  • formulation
  • purity
  • More Info

Description

GNB2L1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 337 amino acids (1-317 and having a molecular mass of 37.2kDa.GNB2L1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

E.coli.

Formulation

The GNB2L1 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 200mM NaCl, 5mM DTT and 50% glycerol.

Purity

Greater than 95% as determined by SDS-PAGE.

More Info

  • Introduction

    GNB2L1 was first known as an anchoring protein for protein kinase C beta (PKCbeta), which it stabilizes in the active state and anchors to membranes or functional sites. But, there is now confirmation that GNB2L1 has an essential part of in critical biological responses. GNB2L1 binds specifically to the active form of PKCbeta isoforms and cooperates with numerous other vital signaling proteins such as the androgen receptor, the Src kinase family, integrin beta1, integrin beta2, integrin beta3 and integrin beta5, beta-spectrin and dynamin, RasGAP, IGF-1r, Epstein-Barr virus trans-activator protein BZLF1, p73 and pRB. GNB2L1 is highly expressed in tissues of higher mammals and humans including spleen, liver and brain.

  • Synonyms

    Guanine nucleotide binding protein (G protein) beta polypeptide 2-like 1, RACK1, Receptor for Activated C Kinase 1, Gnb2-rs1, H12.3, Cell proliferation-inducing gene 21 protein, Guanine nucleotide-binding protein subunit beta-like protein 12.3, Human lung cancer oncogene 7 protein, Receptor of activated protein kinase C 1, HLC-7, PIG21, proliferation-inducing gene 21, protein homologous to chicken B complex protein guanine nucleotide binding.

  • Physical Appearance

    Sterile Filtered colorless solution.

  • Stability

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

  • Amino Acid Sequence

    MGSSHHHHHH SSGLVPRGSH MTEQMTLRGT LKGHNGWVTQ IATTPQFPDM ILSASRDKTI IMWKLTRDET NYGIPQRALR GHSHFVSDVV ISSDGQFALS GSWDGTLRLW DLTTGTTTRR FVGHTKDVLS VAFSSDNRQI VSGSRDKTIK LWNTLGVCKY TVQDESHSEW VSCVRFSPNS SNPIIVSCGW DKLVKVWNLA NCKLKTNHIG HTGYLNTVTV SPDGSLCASG GKDGQAMLWD LNEGKHLYTL DGGDIINALC FSPNRYWLCA ATGPSIKIWD LEGKIIVDEL KQEVISTSSK AEPPQCTSLA WSADGQTLFA GYTDNLVRVW QVTIGTR

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Gnb2L1 Human

You may also like