FCMR Human

FCMR Human

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  • Name :

    FCMR Human

    Description:

    Fc Fragment Of IgM Receptor Human Recombinant

    Fas apoptotic inhibitory molecule 3, IgM Fc fragment receptor, Regulator of Fas-induced apoptosis Toso, FAIM3, TOSO.

    Product # :

    PRO-2579

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  • More Info

Description

FCMR Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain (a.a 18-250) containing 243 amino acids including a 10 a.a N-terminal His tag. The total molecular mass is 27.2kDa (calculated).

Source

Escherichia Coli.

Formulation

FCMR filtered (0.4 µm) and lyophilized from 0.5mg/ml in 50mM acetate buffer, pH 4.

Purity

Greater than 95.0% as determined by SDS-PAGE.

More Info

  • Introduction

    Fas apoptotic inhibitory molecule 3 or FCMR takes part in processes occurring within the immune system. The FCMR is protecting cells from apoptosis that is induced by FADD, FAS and TNF alpha proteins, without over expressing inhibitors of apoptosis such as BCLXL or BCL2. FCMR activates an inhibitory pathway that inhibits CASP8 activation, instead of blocking apoptotic signals downstream.

  • Synonyms

    Fas apoptotic inhibitory molecule 3, IgM Fc fragment receptor, Regulator of Fas-induced apoptosis Toso, FAIM3, TOSO.

  • Physical Appearance

    Filtered White lyophilized (freeze-dried) powder.

  • Stability

    Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

  • Solubility

    It is recommended to add 0.1M acetate buffer, pH 4 to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. In higher concentrations the solubility of this antigen is limited.

  • Amino Acid Sequence

    MKHHHHHHAS RILPEVKVEG ELGGSVTIKC PLPEMHVRIY LCREMAGSGT CGTVVSTTNF IKAEYKGRVT LKQYPRKNLF LVEVTQLTES DSGVYACGAG MNTDRGKTQK VTLNVHSEYE PSWEEQPMPE TPKWFHLPYL FQMPAYASSS KFVTRVTTPA QRGKVPPVHH SSPTTQITHR PRVSRASSVA GDKPRTFLPS TTASKISALE GLLKPQTPSY NHHTRLHRQR ALDYGSQSGR EGQ.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Fcmr Human

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