FCGR2B Human

FCGR2B Human

CD Antigens

Name

Description

Product #

Price

Quantity

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  • Name :

    FCGR2B Human

    Description:

    CD32 Human Recombinant

    CD32, CD32B, FCG2, FCGR2, IGFR2, Low affinity immunoglobulin gamma Fc region receptor II-b, CDw32, Fc-gamma-RIIb, FcRII-b.

    Product # :

    PRO-1295

    Price :

    Quantity :

    Shipping Method :

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  • description
  • source
  • formulation
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  • More Info

Description

FCGR2B Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 197 amino acids (46-217a.a.) and having a molecular mass of 22.0kDa. FCGR2Bis fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Formulation

FCGR2B protein solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 30% glycerol and 1mM DTT.

Purity

Greater than 95.0% as determined by SDS-PAGE.

More Info

  • Introduction

    FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. FCGR2B participates in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. FCGR2B Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Variants in FCGR2B may increase susceptibilty to systemic lupus erythematosus (SLE).

  • Synonyms

    CD32, CD32B, FCG2, FCGR2, IGFR2, Low affinity immunoglobulin gamma Fc region receptor II-b, CDw32, Fc-gamma-RIIb, FcRII-b.

  • Physical Appearance

    Sterile Filtered clear solution.

  • Stability

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

  • Amino Acid Sequence

    MGSSHHHHHH SSGLVPRGSH MGSHMAPPKA VLKLEPQWIN VLQEDSVTLT CRGTHSPESD SIQWFHNGNL IPTHTQPSYR FKANNNDSGE YTCQTGQTSL SDPVHLTVLS EWLVLQTPHL EFQEGETIVL RCHSWKDKPL VKVTFFQNGK SKKFSRSDPN FSIPQANHSH SGDYHCTGNI GYTLYSSKPV TITVQAP.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Fcgr2B Human

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