Elcatonin

Elcatonin

Hormones

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  • Name :

    Elcatonin

    Description:

    Elcatonin

    Product # :

    HOR-302

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    Quantity :

    Shipping Method :

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    Shipped at Room temp

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  • description
  • formulation
  • purity
  • biological activity
  • More Info

Description

Elcatonin Synthetic is a single, non-glycosylated polypeptide chain containing 31 amino acids, having a molecular mass of 3363.2 Dalton and a Molecular formula of C148H244N42O47.

Formulation

The protein was lyophilized with no additives.

Purity

Greater than 93.3% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Biological Activity

Biological Activity (based on net peptide) was found to be 6695.2 IU/mg.

More Info

  • Introduction

    Elcatonin is a Calcitonin derivative which is transformed from eel´s calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. In addition, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis.

  • Physical Appearance

    Sterile Filtered White lyophilized (freeze-dried) powder.

  • Stability

    Lyophilized Elcatonin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Elcatonin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

  • Solubility

    It is recommended to reconstitute the lyophilized Elcatonin in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

  • Amino Acid Sequence

    Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Val-Gly-Ala-Gly-Thr-Pro-NH2.

  • Background

    What is the molecular weight/Mw of ELCATONIN Protein?
    ELCATONIN Protein has a total Mw of 3.36kDa.

    What is the Purity of ELCATONIN Protein?
    ELCATONIN Protein is > 93.3% pure as determined by SDS-PAGE.

    What is the Biological Activity of ELCATONIN Protein?
    Biological Activity (based on net peptide) was found to be 6695.2 IU/mg.

    What is the amino acid sequence of ELCATONIN Protein?
    Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Val-Gly-Ala-Gly-Thr-Pro-NH2.

    What applications can ELCATONIN Protein be used in?
    ELCATONIN Protein can probably be used in western blot, ELISA and Lateral Flow.

    What is the endotoxin level for ELCATONIN Protein?
    The endotoxin level is minimal, ELCATONIN Protein was purified using conventional chromatography techniques.

    Who supplies ELCATONIN that is in stock and available to order?
    ProSpec has the protein in stock and available for immediate delivery.

    Where can I order bulk mg quantities of ELCATONIN?
    ProSpec supplies bulk mg quantities at affordable prices that meets research and academic budgets.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Elcatonin

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