KRT8 Human (421-484)

KRT8 Human (421-484)

Cytokeratin

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Description

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  • Name :

    KRT8 Human (421-484)

    Description:

    Cytokeratin 8 (421-484 a.a) Human Recombinant

    Keratin type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, KRT8, CYK8, KO, CK8, K2C8, CARD2.

    Product # :

    PRO-2839

    Price :

    Quantity :

    Shipping Method :

    Room Temp Icon

    Shipped at Room temp

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  • description
  • source
  • formulation
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  • More Info

Description

The KRT8 Human is created as a recombinant protein with a 4kda N-terminal fusion of His Tag. The KRT8 His-Tagged Fusion Protein, produced in E. coli, is a 10kDa protein containing 64 amino acid residues of the KRT8 Human, 421-484 amino acids.

Source

Escherichia Coli.

Formulation

Each mg was lyophilized with 1xPBS, 0.4% SDS and 4mM DTT.

Purity

Greater than 90% as determined by SDS-PAGE.

More Info

  • Synonyms

    Keratin type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, KRT8, CYK8, KO, CK8, K2C8, CARD2.

  • Physical Appearance

    Filtered White lyophilized (freeze-dried) powder.

  • Stability

    Store lyophilized KRT8 at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

  • Solubility

    It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it on cell culture.

  • Amino Acid Sequence

    GGLSSAYGGL TSPGLSYSLG SSFGSGAGSS SFSRTSSSRA VVVKKIETRD GKLVSESSDV LPK

  • Background

    Cytokeratin 8, also known as KRT8, is a part of the type II keratin family clustered on the long arm of chromosome 12 which plays an important role in the structural integrity of epithelial cells. KRT8 pairs with keratin 18 (a type I keratin) to form heterodimers, which assemble into intermediate filaments. KRT8 takes part in retaining cellular structural integrity and also participates in signal transduction and cellular differentiation.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Cytokeratin 8 Human

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