CXCL11 Human (63-87 a.a.)

CXCL11 Human (63-87 a.a.)

Chemokines

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  • Name :

    CXCL11 Human (63-87 a.a.)

    Description:

    ITAC (63-87 a.a.) Human Recombinant

    ITAC, I-TAC, CXCL-11, CXCL11.

    Product # :

    CHM-049

    Price :

    Quantity :

    Shipping Method :

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    Shipped at Room temp

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Description

The I-TAC Human is created as a recombinant protein with a 4kda N-terminal fusion of His Tag. The I-TAC His-Tagged Fusion Protein, produced in E. coli, is a 9kDa protein containing 25 amino acid residues of the I-TACHuman, 63-87 amino acids.

Source

Escherichia Coli.

Formulation

Each mg was lyophilized with 1xPBS, 0.4% SDS and 4mM DTT.

Purity

Greater than 90% as determined by SDS-PAGE.

More Info

  • Synonyms

    ITAC, I-TAC, CXCL-11, CXCL11.

  • Physical Appearance

    Filtered White lyophilized (freeze-dried) powder.

  • Stability

    Store lyophilized I-TAC at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

  • Solubility

    It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it on cell culture.

  • Background

    I-TAC is a small cytokine belongs to the CXC chemokinen family which also called inducible T-cell alpha chemoattractant and IP-9. I-TAC is expressed mainly in peripheral blood leukocytes, liver and pancreas with moderate levels in spleen, thymus and lung and low levels in small intestine, placenta and prostate. IFN-g and IFN-b induces strongly gene expression of I-TAC. The I-TAC chemokine elicits its effects on its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9 and CXCL10.

    What is the molecular weight/Mw of CXCL11 HUMAN (63-87 A.A.) Protein?
    CXCL11 HUMAN (63-87 A.A.) Protein has a total Mw of 9kDa.

    What is the source or expression system of CXCL11 HUMAN (63-87 A.A.) Protein?
    Escherichia Coli.

    What is the Purity of CXCL11 HUMAN (63-87 A.A.) Protein?
    CXCL11 HUMAN (63-87 A.A.) Protein is >90% pure as determined by SDS-PAGE.

    What is the Biological Activity of CXCL11 HUMAN (63-87 A.A.) Protein?
    The biological functionality of CXCL11 HUMAN (63-87 A.A.) Protein will be determined in the future.

    What is the amino acid sequence of CXCL11 HUMAN (63-87 A.A.) Protein?
    CXCL11 HUMAN (63-87 A.A.) Protein is composed from 25 amino acids.

    What applications can CXCL11 HUMAN (63-87 A.A.) Protein be used in?
    CXCL11 HUMAN (63-87 A.A.) Protein can probably be used in western blot, ELISA and Lateral Flow.

    What is the endotoxin level for CXCL11 HUMAN (63-87 A.A.) Protein?
    The endotoxin level is minimal, CXCL11 HUMAN (63-87 A.A.) Protein was purified using conventional chromatography techniques.

    Who supplies recombinant CXCL11 HUMAN (63-87 A.A.) that is in stock and available to order?
    ProSpec has the protein in stock and available for immediate delivery.

    Where can I order bulk mg quantities of CXCL11 HUMAN (63-87 A.A.)?
    ProSpec supplies bulk mg quantities at affordable prices that meets research and academic budgets.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Cxcl11 Human

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Frequently asked questions

1. Which company offers Recombinant Chemokines at competitive prices?

ProSpec offers vast array of Chemokines such as Eotaxin | Fractalkine | IL-8 | Rantes and much more at affordable descent prices to meet academic budgets
ProSpec provides High Purity Chemokines for 30 years, purity exhibits 95% and more as visualized by SDS-PAGE gel.
Chemokines are in stock for immediate delivery via FedEx which enables scientists and researchers to perform immediate experiments.
Chemokines are shipped globally using ProSpec’s custom tailored Styrofoam insulated box and premium ice packs that ensure maximum protein stability during transit to your laboratory.

2. Who can produce a custom Chemokine ?

ProSpec custom produces recombinant chemokines starting from Gene Design, Gene cloning, Expression Screening, Fermentation + protein expression, Cell harvesting + disruption, Protein recovery and purification to Q.C. formulation and filling, lyophilization is offered as an option.

3. What is the production time for a custom Chemokine?

The production time for a custom recombinant chemokine protein may vary between 5-7 weeks.

4. Where can i find biologically active Chemokines?

ProSpec offers biologically functional Chemokines such as SDF1A | Platelet Factor-4 | MCP1 which are rigorously tested in-vitro to provide researchers world wide BioActive Chemokines.

5. What is the difference between CC, CXC, CX3C, and XC chemokines?

Chemokines are a superfamily of small, secreted signaling proteins that direct the migration of immune cells, they are classified into 4 subfamilies based on the spacing of the cysteine residues near their N-terminus. CC and CXC are the largest families, while CX3C and XC contain fewer members. You can find CXC chemokines and CC chemokines at ProSpecBio such as cat# chm-348 Recombinant Human BCA-1/ BLC (CXCL13), cat# chm-001, Recombinant Human BRAK (CXCL14), cat#
chm-029, Recombinant Human CXCL16, cat# chm-331 Recombinant Human ENA78 (CXCL5) and more....

6. Which receptors bind to a specific chemokine?

Chemokines mainly bind G-protein-coupled receptors ( GPCR ), located on the surfaces of target cells. They match the structural classification of their ligands. Chemokines bind more than one receptor. For instance, CCL2 primarily binds CCR2, while CXCL12 binds CXCR4 and ACKR3. You can find CCL2 chemokine at ProSpecBio cat# chm-271, MCP1.