CHRNA3 Human

CHRNA3 Human

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  • Name :

    CHRNA3 Human

    Description:

    Cholinergic Receptor Nicotinic Alpha 3 Human Recombinant

    Cholinergic Receptor, Nicotinic, Alpha 3 (Neuronal), Cholinergic Receptor, Nicotinic, Alpha Polypeptide 3, NACHRA3, LNCR2, PAOD2, Neuronal Nicotinic Acetylcholine Receptor, Alpha3 Subunit, Neuronal Acetylcholine Receptor Subunit Alpha-3, Acetylcholine Receptor, Alpha 3 (Neuronal), Nicotinic, Neuronal acetylcholine receptor subunit alpha-3.

    Product # :

    PRO-2216

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  • More Info

Description

CHRNA3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 232 amino acids (32-240 a.a) and having a molecular mass of 27kDa. CHRNA3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Formulation

CHRNA3 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0) and 10% glycerol.

Purity

Greater than 80.0% as determined by SDS-PAGE.

More Info

  • Introduction

    Cholinergic Receptor Nicotinic Alpha 3, also known as CHRNA3 is part of the nicotinic acetylcholine receptor family. Proteins of this family form pentameric complexes comprised of both alpha & beta subunits. Furthermore, CHRNA3 is ligand-gated ions channel which prticipates in neurotransmission. CHRNA3 has been associated with an increased risk of smoking initiation as well as an increased susceptibility to lung cancer.

  • Synonyms

    Cholinergic Receptor, Nicotinic, Alpha 3 (Neuronal), Cholinergic Receptor, Nicotinic, Alpha Polypeptide 3, NACHRA3, LNCR2, PAOD2, Neuronal Nicotinic Acetylcholine Receptor, Alpha3 Subunit, Neuronal Acetylcholine Receptor Subunit Alpha-3, Acetylcholine Receptor, Alpha 3 (Neuronal), Nicotinic, Neuronal acetylcholine receptor subunit alpha-3.

  • Physical Appearance

    Sterile Filtered clear solution.

  • Stability

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

  • Amino Acid Sequence

    MGSSHHHHHH SSGLVPRGSH MGSSEAEHRL FERLFEDYNE IIRPVANVSD PVIIHFEVSM SQLVKVDEVN QIMETNLWLK QIWNDYKLKW NPSDYGGAEF MRVPAQKIWK PDIVLYNNAV GDFQVDDKTK ALLKYTGEVT WIPPAIFKSS CKIDVTYFPF DYQNCTMKFG SWSYDKAKID LVLIGSSMNL KDYWESGEWA IIKAPGYKHD IKYNCCEEIY PDITYSLYIR RL.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Chrna3 Human

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