CD68 Human

CD68 Human

CD Antigens

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  • Name :

    CD68 Human

    Description:

    CD68 Human Recombinant

    Macrosialin, Gp110, CD68 antigen, CD68, SCARD1, DKFZp686M18236.

    Product # :

    PRO-1209

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  • source
  • formulation
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  • More Info

Description

CD68 Human Recombinant produced in E. coli is a single polypeptide chain containing 323 amino acids (22-319) and having a molecular mass of 34.1 kDa.CD68 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

E.coli.

Formulation

The CD68 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 1M Urea and 10% glycerol.

Purity

Greater than 85% as determined by SDS-PAGE.

More Info

  • Introduction

    CD68 encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

  • Synonyms

    Macrosialin, Gp110, CD68 antigen, CD68, SCARD1, DKFZp686M18236.

  • Physical Appearance

    Sterile Filtered colorless solution.

  • Stability

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

  • Amino Acid Sequence

    MGSSHPLHHH SSGLVPRGSH MGSHMNDCPH KKSATLLPSF TVTPTVTEST GTTSHRTTKS HKTTTHRTTT TGTTSHGPTT ATHNPTTTSH GNVTVHPTSN STATSQGPST ATHSPATTSH GNATVHPTSN STATSPGFTS SAHPEPPPPS PSPSPTSKET IGDYTWTNGS QPCVHLQAQI QIRVMYTTQG GGEAWGISVL NPNKTKVQGS CEGAHPHLLL SFPYGHLSFG FMQDLQQKVV YLSYMAVEYN VSFPHAAQWT FSAQNASLRD LQAPLGQSFS CSNSSIILSP AVHLDLLSLR LQAAQLPHTG VFGQSFSCPS DRS

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Cd68 Human

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