CD46 Antibody

CD46 Antibody

Anti Human Lymphocyte

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Description

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Price

Quantity

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  • Name :

    CD46 Antibody

    Description:

    CD46, Mouse Anti Human

    AHUS2, MCP, MIC10, TLX, TRA2.10, Membrane cofactor protein, Trophoblast leukocyte common antigen, CD46.

    Product # :

    ANT-552

    Price :

    Quantity :

    Shipping Method :

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    Shipped with Ice Packs

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  • formulation
  • More Info

Formulation

1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.

More Info

  • Introduction

    Membrane cofactor protein isoform 14 (CD46), is a type I membrane protein which has cofactor activity for inactivation of complement components C3b and C4b by serum factor I. This function resides in the complement control protein repeats (CCPs), with CCP1–4 vital for regulation. CD46 is also involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 is common in thymocytes, T cells, B cells, monocytes, granulocytes, NK cells, platelets, endothelial cells, epithelial cells, fibroblasts, placenta and sperm.

  • Synonyms

    AHUS2, MCP, MIC10, TLX, TRA2.10, Membrane cofactor protein, Trophoblast leukocyte common antigen, CD46.

  • Physical Appearance

    Sterile filtered colorless solution.

  • Immunogen

    Anti-human CD46 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CD46 protein 35-313 amino acids purified from E. coli.

  • Ig Subclass

    Mouse IgG2a heavy chain and k light chain.

  • Clone

    PAT2G9AT.

  • Applications

    CD46 antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

  • Type

    Mouse Anti Human Monoclonal.

  • Storage Procedures

    For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

  • Purification Method

    CD46 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Cd46 Antibody

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