CD40 Antibody, Biotin

CD40 Antibody, Biotin

Anti Human Lymphocyte

Name

Description

Product #

Price

Quantity

Shipping Method

  • Name :

    CD40 Antibody, Biotin

    Description:

    CD40, Mouse Anti-Human, Biotin

    p50, Bp50, CDW40, MGC9013, TNFRSF5, CD40.

    Product # :

    ANT-264

    Price :

    Quantity :

    Shipping Method :

    Room Temp Icon

    Shipped at Room temp

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  • formulation
  • More Info

Formulation

1mg/ml in PBS (after reconstitution).

More Info

  • Introduction

    CD40 is part of the TNF-receptor superfamily. CD40 is a necessary mediator for vast range of immune and inflammatory responses together with T cell-dependent immunoglobulin class switching, memory B cell growth, and germinal center formation. The transcription factor AKNA regulates the expression of CD40 and its ligand, which is vital for homotypic cell interactions. Adaptor protein TNFR2 interacts with CD40 and serves as a mediator of the signal transduction. The interaction of CD40 and its ligand is crucial for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is the receptor for TNFSF5/CD40L.

  • Synonyms

    p50, Bp50, CDW40, MGC9013, TNFRSF5, CD40.

  • Solubility

    Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

  • Immunogen

    Activated Human B cells.

  • Ig Subclass

    Mouse IgG1.

  • Clone

    hCD40.

  • Applications

    Staining antibody. For staining, use 10µl/1,000,000 cells.

  • Available Conjugates

    This antibody is also available unconjugated and conjugated to FITC. For staining with biotin or FITC-conjugated antibody use 5-10µl/106 cells.

  • Type

    Mouse Anti Human Monoclonal.

  • Storage Procedures

    Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

  • Purification Method

    Protein-A.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Cd40 Antibody Biotin

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