CD11b Antibody, FITC

CD11b Antibody, FITC

Anti Human Lymphocyte

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  • Name :

    CD11b Antibody, FITC

    Description:

    CD11b, Mouse Anti-Human, FITC

    Integrin alpha-M, Cell surface glycoprotein MAC-1 subunit alpha, CR-3 alpha chain, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD11b antigen, ITGAM, CR3A, MO1A, CD11B, MAC-1, MAC1A, MGC117044.

    Product # :

    ANT-276

    Price :

    Quantity :

    Shipping Method :

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    Shipped at Room temp

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  • formulation
  • More Info

Formulation

1mg/ml in PBS (after reconstitution).

More Info

  • Introduction

    Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Integrin alpha-m/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. CD-11b is identical with cr-3, the receptor for the ic3b fragment of the third complement component. CD-11b probably recognizes the r-g-d peptide in c3b. Integrin alpha-m/beta-2 is also a receptor for fibrinogen, factor x and icam1. it recognizes p1 and p2 peptides of fibrinogen gamma chain.

  • Synonyms

    Integrin alpha-M, Cell surface glycoprotein MAC-1 subunit alpha, CR-3 alpha chain, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD11b antigen, ITGAM, CR3A, MO1A, CD11B, MAC-1, MAC1A, MGC117044.

  • Solubility

    Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

  • Immunogen

    Purified human PBL Monocytes.

  • Ig Subclass

    Mouse IgG1.

  • Clone

    hCD11b.

  • Applications

    Blocking and staining antibody. For staining, use 10µl/1,000,000 cells. Titer for blocking LPS binding should be determined by the investigator.

  • Available Conjugates

    This antibody is also available unconjugated and conjugated to Biotin. For staining with biotin or FITC-conjugated antibody use 5-10µl/1,000,000 cells.

  • Type

    Mouse Anti Human Monoclonal.

  • Storage Procedures

    Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

  • Purification Method

    Ion exchange column.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Cd11B Antibody Fitc

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