C1S Human

C1S Human

Complement Component

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  • Name :

    C1S Human

    Description:

    Complement C1s Human

    Complement C1s subcomponent, C1 esterase, Complement component 1 subcomponent s, C1S.

    Product # :

    ENZ-1164

    Price :

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  • description
  • source
  • formulation
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  • More Info

Description

Human Complement C1s produced in Human plasma having a molecular mass of 86 kDa.

Source

Human Plasma.

Formulation

The protein contains PBS.

Purity

Greater than 95.0% as determined by SDS-PAGE.

More Info

  • Introduction

    C1s enzyme (a subunit of the C1 complex) is the activated form of C1s proenzyme which is the first complement component in the classical pathway of complement. C1s proenzyme is an inactive zymogen until C1 is activated. C1 is a non-covalent calcium-dependent complex containing1 C1q, 2 C1r and 2 C1s molecules.The binding of multiple arms to immune complexes causesthe production of 2 proteases that cleave and activate the 2 C1s protease zymogens in the complex by the C1r proteins. This activation of C1s proenzyme results in its cleavage into 2 C1s chains of 58,000 and 28,000 Dalton.

  • Synonyms

    Complement C1s subcomponent, C1 esterase, Complement component 1 subcomponent s, C1S.

  • Physical Appearance

    Sterile Filtered solution.

  • Stability

    Human C1s is stable at 4°C if entire vial will be used within 2-4 weeks.Store, frozen below -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

  • Human Virus Test

    Plasma from each donor has been tested and found negative for antibody to HIV-1, HIV-2, HCV, HTLV-I &II, STS and HBSAG.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

C1S Human

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