C-Myc (410-419aa) Antibody

C-Myc (410-419aa) Antibody

Monoclonal Antibodies

Name

Description

Product #

Price

Quantity

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  • Name :

    C-Myc (410-419aa) Antibody

    Description:

    c-Myc (410-419aa), Mouse Anti Human

    MYC, CMYC, C-MYS, V-MYC, P64.

    Product # :

    ANT-618

    Price :

    Quantity :

    Shipping Method :

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  • formulation
  • More Info

Formulation

1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.

More Info

  • Introduction

    c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

  • Synonyms

    MYC, CMYC, C-MYS, V-MYC, P64.

  • Physical Appearance

    Sterile filtered colorless solution.

  • Immunogen

    Anti-human C-Myc mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human C-Myc protein 410-419 amino acids purified from E. coli.

  • Ig Subclass

    Mouse IgG1 heavy chain and k light chain.

  • Clone

    PAT19B4AT.

  • Applications

    The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

  • Type

    Mouse Anti Human Monoclonal.

  • Storage Procedures

    For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

  • Purification Method

    C-Myc antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

C Myc 410 419Aa Antibody

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