AMH (452-560) Human

AMH (452-560) Human

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  • Name :

    AMH (452-560) Human

    Description:

    Anti-Mullerian Hormone (452-560) Human Recombinant

    Anti-Muellerian hormone, AMH, Muellerian-inhibiting substance, MIS, MIF. 

    Product # :

    PRO-2843

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    Shipped at Room temp

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  • source
  • formulation
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  • biological activity
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Description

Anti-Mullerian Hormone Human Recombinant produced in CHO is a Homodimer, glycosylated, polypeptide chain containing 109 amino acids (Ser452-Arg560) and having a total molecular mass of 23.4Da.

Anti-Mullerian Hormone is purified by proprietary chromatographic techniques.

Source

CHO Cells.

Formulation

AMH Lyophilized from a 0.2µm filtered solution in 35% (v/v) Acetonitrile and 0.1% (v/v) TFA.

Purity

Greater than 97% as determined by SDS-PAGE and SEC-HPLC analyses.

Biological Activity

Immobilized Recombinant Human AMH at 3 µg/mL (100 µL/well) will bind Recombinant Human MIS RII Fc Chimera with a linear range of 2.0-100 ng/mL. The activity was measured by its binding ability in a functional ELISA.

More Info

  • Introduction

    Anti-Mullerian Hormone also known as AMH is a member of the TGF-beta family. AMH is a glycoprotein which is produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. AMH inhibits the growth of tumors derived from tissues of Muellerian duct origin. Moreover, AMH participates in Leydig cell differentiation and function in addition to follicular development in adult females.

  • Synonyms

    Anti-Muellerian hormone, AMH, Muellerian-inhibiting substance, MIS, MIF.

  • Physical Appearance

    Filtered White lyophilized (freeze-dried) powder.

  • Stability

    Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

  • Solubility

    It is recommended to reconstitute in sterile 4mM HCl to a concentration of 100µg/ml, which can then be further diluted to other aqueous solutions.

  • Amino Acid Sequence

    SAGATAADGP CALRELSVDL RAERSVLIPE TYQANNCQGV CGWPQSDRNP RYGNHVVLLL KMQVRGAALA RPPCCVPTAY AGKLLISLSE ERISAHHVPN MVATECGCR.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Anti Mullerian Hormone Cho

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