ALDH6A1 Human

ALDH6A1 Human

Dehydrogenase

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  • Name :

    ALDH6A1 Human

    Description:

    Aldehyde Dehydrogenase 6 A1 Human Recombinant

    MMSADHA, MMSDH , Aldehyde Dehydrogenase 6 Family, Member A1, Methylmalonate-Semialdehyde Dehydrogenase [Acylating], Mitochondrial, Mitochondrial Acylating Methylmalonate-Semialdehyde Dehydrogenase, Malonate-Semialdehyde Dehydrogenase [Acylating], Aldehyde Dehydrogenase Family 6 Member A1, Malonate-Semialdehyde Dehydrogenase, EC 1.2.1.18, EC 1.2.1.27.

    Product # :

    ENZ-907

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  • formulation
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  • More Info

Description

ALDH6A1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 525 amino acids (34-535 a.a) and having a molecular mass of 56.8kDa. ALDH6A1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Formulation

ALDH6A1 protein solution (0.25mg/ml) containing Phosphate buffered saline (pH7.4), 10% glycerol and 1mM DTT.

Purity

Greater than 85.0% as determined by SDS-PAGE.

More Info

  • Introduction

    ALDH6A1 or Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial is a mitochondrial methylmalonate semialdehyde dehydrogenase. ALDH6A1 participates in the valine and pyrimidine catabolic pathways. ALDH6A1 catalyzes the irreversible oxidative decarboxylation of malonate, propionyl-CoA and methylmalonate semialdehydes to acetyl. ALDH6A1 deficiency is distinguished by high levels of beta-alanine, 3-hydroxypropionic acid, and the two isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.

  • Synonyms

    MMSADHA, MMSDH , Aldehyde Dehydrogenase 6 Family, Member A1, Methylmalonate-Semialdehyde Dehydrogenase [Acylating], Mitochondrial, Mitochondrial Acylating Methylmalonate-Semialdehyde Dehydrogenase, Malonate-Semialdehyde Dehydrogenase [Acylating], Aldehyde Dehydrogenase Family 6 Member A1, Malonate-Semialdehyde Dehydrogenase, EC 1.2.1.18, EC 1.2.1.27.

  • Physical Appearance

    Sterile Filtered colorless solution.

  • Stability

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

  • Amino Acid Sequence

    MGSSHHHHHH SSGLVPRGSH MGSSSSVPTV KLFIGGKFVE SKSDKWIDIH NPATNEVIGR VPQATKAEMD AAIASCKRAF PAWADTSVLS RQQVLLRYQQ LIKENLKEIA KLITLEQGKT LADAEGDVFR GLQVVEHACS VTSLMMGETM PSITKDMDLY SYRLPLGVCA GIAPFNFPAM IPLWMFPMAM VCGNTFLMKP SERVPGATML LAKLLQDSGA PDGTLNIIHG QHEAVNFICD HPDIKAISFV GSNKAGEYIF ERGSRHGKRV QANMGAKNHG VVMPDANKEN TLNQLVGAAF GAAGQRCMAL STAVLVGEAK KWLPELVEHA KNLRVNAGDQ PGADLGPLIT PQAKERVCNL IDSGTKEGAS ILLDGRKIKV KGYENGNFVG PTIISNVKPN MTCYKEEIFG PVLVVLETET LDEAIQIVNN NPYGNGTAIF TTNGATARKY AHLVDVGQVG VNVPIPVPLP MFSFTGSRSS FRGDTNFYGK QGIQFYTQLK TITSQWKEED ATLSSPAVVM PTMGR.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Aldh6A1 Human

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