AKR1A1 Human

AKR1A1 Human

Enzymes

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  • Name :

    AKR1A1 Human

    Description:

    Aldo-Keto Reductase Family 1 Member A1 Human Recombinant

    Alcohol dehydrogenase, ALR, ARM, DD3, ALDR1, MGC1380, MGC12529, AKR1A1, Alcohol dehydrogenase [NADP+], Aldehyde reductase, Aldo-keto reductase family 1 member A1.

    Product # :

    ENZ-464

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  • More Info

Description

AKR1A1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 325 amino acids (1-325 a.a.) and having a molecular mass of 36.5 kDa. AKR1A1 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Formulation

AKR1A1 solution containing 20mM Tris pH-8, 50mM NaCl and 10% glycerol.

Purity

Greater than 90% as determined by SDS-PAGE.

More Info

  • Introduction

    AKR1A1 is part of the aldo/keto reductase superfamily, it catalyzes the NADPH-dependent reduction from a range of aromatic and aliphatic aldehydes to their related alcohols. AKR1A1 corresponds (65% identity) to aldose reductase, an enzyme that takes part in the pathogenesis of some diabetic and galactosemic complications. AKR1A1 is involved in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs.

  • Synonyms

    Alcohol dehydrogenase, ALR, ARM, DD3, ALDR1, MGC1380, MGC12529, AKR1A1, Alcohol dehydrogenase [NADP+], Aldehyde reductase, Aldo-keto reductase family 1 member A1.

  • Physical Appearance

    Sterile filtered colorless solution.

  • Stability

    AKR1A1 Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.

  • Amino Acid Sequence

    MAASCVLLHT GQKMPLIGLG TWKSEPGQVK AAVKYALSVG YRHIDCAAIY GNEPEIGEAL KEDVGPGKAV PREELFVTSK LWNTKHHPED VEPALRKTLA DLQLEYLDLY LMHWPYAFER GDNPFPKNAD GTICYDSTHY KETWKALEAL VAKGLVQALG LSNFNSRQID DILSVASVRP AVLQVECHPY LAQNELIAHC QARGLEVTAY SPLGSSDRAW RDPDEPVLLE EPVVLALAEKYGRSPAQILL RWQVQRKVIC IPKSITPSRI LQNIKVFDFT FSPEEMKQLN ALNKNWRYIV PMLTVDGKRV PRDAGHPLYP FNDPY

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Akr1A1 Human

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