ACY1 Antibody

ACY1 Antibody

Anti Human Enzyme

Name

Description

Product #

Price

Quantity

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  • Name :

    ACY1 Antibody

    Description:

    AminoAcylase-1, Mouse Anti Human

    ACY1D, ACYLASE, ACY-1, EC 3.5.1.143.

    Product # :

    ANT-555

    Price :

    Quantity :

    Shipping Method :

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  • formulation
  • More Info

Formulation

1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.

More Info

  • Introduction

    ACY1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and acyl group, and has been postulated to take part in the catabolism and salvage of acylated amino acids. Defects in ACY1 are the source of aminoacylase-1 deficiency (ACY1D). ACY1D results in a metabolic disorder manifesting with encephalopathy, unspecific psychomotor delay, psychomotor delay with atrophy of the vermis and syringomyelia, marked muscular hypotonia or normal clinical features. Epileptic seizures are a frequent feature.

  • Synonyms

    ACY1D, ACYLASE, ACY-1, EC 3.5.1.143.

  • Physical Appearance

    Sterile filtered colorless solution.

  • Immunogen

    Anti-human ACY1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human ACY1 amino acids 1-408 purified from E. coli.

  • Ig Subclass

    Mouse IgG2b heavy chain and ? light chain.

  • Clone

    PAT1E2AT.

  • Applications

    ACY1 antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

  • Type

    Mouse Anti Human Monoclonal.

  • Storage Procedures

    For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

  • Purification Method

    ACY1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Acy1 Antibody

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