Search results

73 results found for “POU Class”

Name

Description

Product #

Price

Quantity

Shipping Method

  • View Data Sheet

    Description:

    Immunoglobulin-M Human

    Product # :

    PRO-2745

    Price :

    Quantity :

    Shipping Method :

    Ice Icon

    Shipped with Ice Packs

    Add To Cart

    More Info

    • description
    • source
    • formulation
    • purity
    • More Info

    Description

    Human Immunoglobulin-M produced in human plasma having a molecular mass of 950kDa.

    Source

    Human plasma.

    Formulation

    IgM solution (1.98mg/ml) contains 50mM TRIS buffer, pH 8.0, 0.2M NaCl and 0.05% NaN3.

    Purity

    Greater than 95.0%.

    More Info

    • Introduction

      Immunoglobulin M (IgM) is a basic antibody produced by B cells. IgM is the first antibody to emerge in response to initial exposure to an antigen. IgM antibodies are found in the blood and lymph fluid and are the third most widespread serum Ig. Immunoglobulin M (IgM), being the 3rd most widespread serum Ig and exists in two forms- mostly as a pentamer (970kDa) but also as a hexamer. The pentameric IgM has 10 binding sites since each monomer has two antigen binding sites. Due to distance constraints in the hexameric complex, the J chain is found in pentameric IgM but not in the hexameric form. IgM antibodies, which appear early in the course of an infection, typically reappear to a smaller extent after additional exposure. IgM, as opposed to IgG antibodies, do not pass across the human placenta. These properties of IgM make it suitable for the diagnosis of infectious diseases.

    • Physical Appearance

      Sterile Filtered solution.

    • Stability

      Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

    • Human Virus Test

      Human Immunoglobulin-M has been tested and certified negative for antibodies to HIV-1, HIV-2, anti-HBc, HCV and HBSAG.

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

    Igm Human