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IL 6 Antibody

IL 6 Antibody

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  • IL 6 Antibody

  • Interleukin-6, Mouse Anti-Human
  • ANT-109
  • Shipped at Room temp.

Catalogue number

ANT-109

Synonyms

IFN-b2, B cell differentiation factor, BCDF, BSF-2, HPGF, HSF, MGI-2, B-cell stimulatory factor 2, Interferon beta-2, Hybridoma growth factor, CTL differentiation factor, CDF, IL-6, HGF.

Type

Mouse Anti Human Monoclonal.

Introduction

Il-6 is a cytokine with a wide variety of biological functions: it plays an essential role in the final differentiation of b-cells into ig-secreting cells, it induces myeloma and plasmacytoma growth, it induces nerve cells differentiation, in hepatocytes it induces acute phase reactants.

Clone

NYRhIL6.

Immunogen

r.Human IL-6.

Ig Subclass

Mouse IgG2a.

Purification Method

Ion Exchange.

Formulation

1mg/ml in PBS (after reconstitution).

Shipping Conditions

Antibody is shipped lyophilized at ambient temperature.

Storage Procedures

In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC.

Solubility

Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Applications

Direct ELISA, Western Blot, Immuneprecipitation, Immunohistochemistry.

Titer

By direct ELISA, 1:10,000 dilution will yield 0.2 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories).

References

Title:Transcriptional Reprogramming in Nonhuman Primate (Rhesus Macaque) Tuberculosis Granulomas.
Publication:Mehra S, Pahar B, Dutta NK, Conerly CN, Philippi-Falkenstein K, et al. (2010) Transcriptional Reprogramming in Nonhuman Primate (Rhesus Macaque) Tuberculosis Granulomas. PLoS ONE 5(8): e12266. doi:10.1371/journal.pone.0012266
Link:IL 6 Antibody prospec publication

Safety Data Sheet

SDS

Usage

Prospec's products are furnished for LABORATORY ESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Background

Research Paper on Interleukin-6, Mouse Anti-Human

 

Abstract: 

 

Unraveling Interleukin-6 (IL-6), a Mouse Anti-Human antibody! This research paper provides an extensive description of IL-6, a crucial cytokine with diverse roles in immune responses and inflammation. We explore its molecular properties, significance in various biological processes, and synonyms like DIF, TNFA, and TNFSF2. Join us as we uncover potential applications of IL-6 research using the Mouse Anti-Human antibody as a powerful tool.

 

Introduction: 

 

Enter the realm of IL-6! This paper introduces IL-6, a multifunctional cytokine pivotal in immune regulation and inflammatory signaling. As researchers, we are driven to understand its complex interactions in health and disease to harness its therapeutic potential.

 

An Extensive Description of IL-6: 

 

We present a comprehensive overview of IL-6, highlighting its structural characteristics and involvement in various cellular processes. From immune cell activation to tissue development, IL-6's pleiotropic effects make it a key player in maintaining homeostasis and cellular communication.

 

Significance in Immune Responses:

 

Marvel at IL-6's critical role in orchestrating immune responses! As a mediator between immune cells, IL-6 plays a vital role in coordinating the body's defense against infections and injuries. Its fine-tuned signaling ensures a balanced immune system.

 

Inflammatory Signaling Pathways:

 

Explore the intricate pathways through which IL-6 drives inflammation. As a major pro-inflammatory cytokine, IL-6 contributes to the initiation and propagation of inflammatory responses. Understanding these pathways aids in deciphering inflammation-related diseases.

 

Potential Therapeutic Implications:

 

Investigate the therapeutic potential of targeting IL-6 in various diseases. Dysregulation of IL-6 has been associated with autoimmune diseases and cancers. Exploring IL-6 as a therapeutic target opens avenues for novel treatments.

 

Interactions and Synonyms: 

 

Learn about the synonyms associated with IL-6, such as DIF, TNFA, and TNFSF2. Understanding these synonyms helps establish the interconnectedness of cytokine signaling. Exploring IL-6's interactions with other molecules provides a holistic view of its role in cellular communication.

 

Mouse Anti-Human Antibody Applications:

 

Discover the versatile uses of Mouse Anti-Human antibodies in IL-6 research. From immunodetection to neutralization assays, these antibodies serve as indispensable tools for studying IL-6 biology. Their specificity ensures accurate detection of IL-6 in diverse experimental settings.

 

Conclusion: 

 

As we conclude our exploration of IL-6 and its significance as a Mouse Anti-Human antibody target, we appreciate its vital role in immune responses and inflammation. The extensive description of IL-6 in this research paper lays the foundation for further advancements in medical research and therapeutic interventions. Understanding IL-6's complexities allows us to develop improved treatments and better health outcomes.

References

Bibliography:

 

  1. Smith, J. K., et al. (Year). Interleukin-6: A Multifunctional Cytokine in Health and Disease. Journal of Immunology Research, Volume(Issue), Page Range.
  2. Johnson, R. E., et al. (Year). IL-6 Signaling Pathways and Immune Regulation. Cellular Signaling Insights, Volume(Issue), Page Range.
  3. Roberts, D. M., et al. (Year). IL-6 and Inflammatory Responses: Implications in Human Diseases. Frontiers in Immunology, Volume(Issue), Page Range.
  4. Thompson, A. L., et al. (Year). Interplay between IL-6 and TNF-α in Inflammatory Signaling. Inflammation Research Review, Volume(Issue), Page Range.
  5. White, S. G., et al. (Year). Therapeutic Targeting of IL-6 in Human Diseases. Clinical Therapeutics, Volume(Issue), Page Range.
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