- Name
- Description
- Cat#
- Pricings
- Quantity
Catalogue number
PRO-2819
Synonyms
FZ-10, CD350, Fz10, FzE7, frizzled-10, hFz10, FZD10, frizzled class receptor 10.
Description
FZD10 Human Recombinant is a single, glycosylated, polypeptide chain (21-225 a.a) containing a total of 444 amino acids and having a molecular mass of 50.0 kDa.
FZD10is fused to a 239 a.a hIgG-His-Tag at C-terminus and is purified by proprietary chromatographic techniques.
Source
HEK293 Cells.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
The FZD10 solution (0.5mg/ml) contains 10% Glycerol and Phosphate-Buffered Saline (pH 7.4).
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
ISSMDMERPG DGKCQPIEIP MCKDIGYNMT RMPNLMGHEN QREAAIQLHE FAPLVEYGCH GHLRFFLCSL YAPMCTEQVS TPIPACRVMC EQARLKCSPI MEQFNFKWPD SLDCRKLPNK NDPNYLCMEA PNNGSDEPTR GSGLFPPLFR PQRPHSAQEH PLKDGGPGRG GCDNPGKFHH VEKSASCAPL CTPGVDVYWS REDKRLEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALPAPIEKTISKA KGQPREPQVY TLPPSRDELT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGKHH HHHH.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Background
Frizzled-10 (FZD10) is a member of the Frizzled family of G protein-coupled receptors (GPCRs) that play critical roles in the Wnt signaling pathway, which is essential for various developmental processes, cell proliferation, and differentiation. Recombinant human FZD10 (rhFZD10) has been developed to facilitate research into its biological functions and potential therapeutic applications, particularly in the context of cancer and regenerative medicine. This paper provides a comprehensive overview of the scientific research on recombinant human FZD10, focusing on its biological functionality, detailed description, and physical properties.
Recombinant human FZD10 is primarily used to investigate the role of FZD10 in Wnt signaling and its implications in health and disease.