- Name
- Description
- Cat#
- Pricings
- Quantity
Catalogue number
PRO-2587
Synonyms
Transferrin Receptor, P90, T9, TR, Transferrin Receptor (P90, CD71), Transferrin Receptor Protein 1, CD71 Antigen, IMD46, CD71, TFR1.
Introduction
The Transferrin glycoproteins are responsible for the blood levels of free iron by binding to iron in the plasma. The transferrin molecules in humans are encoded by a gene called TF. Transferrin binds to iron in a tight but reversible way. The iron levels that binds to transferrin are very low in comparison to the total body iron, nonetheless, it is extremely vital iron levels with the greatest turnover rate.
Description
TFRC produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 669 amino acids (101-760a.a.) and having a molecular mass of 74.9kDa. (Molecular size on SDS-PAGE will appear at approximately 70-100kDa). TFRC is expressed with a 9 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques
Source
Sf9, Baculovirus cells.
Physical Appearance
Sterile Filtered clear solution.
Formulation
TFRC protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
ADPLAGTESP VREEPGEDFP AARRLYWDDL KRKLSEKLDS TDFTGTIKLL NENSYVPREA GSQKDENLAL Recombinant Human TFRC Protein Catalog Number: ATGP3825 YVENQFREFK LSKVWRDQHFVKIQVKDSAQ NSVIIVDKNG RLVYLVENPG GYVAYSKAAT VTGKLVHANF GTKKDFEDLY TPVNGSIVIV RAGKITFAEK VANAESLNAI GVLIYMDQTK FPIVNAELSF FGHAHLGTGD PYTPGFPSFN HTQFPPSRSS GLPNIPVQTI SRAAAEKLFG NMEGDCPSDW KTDSTCRMVTSESKNVKLTV SNVLKEIKIL NIFGVIKGFV EPDHYVVVGA QRDAWGPGAA KSGVGTALLL KLAQMFSDMV LKDGFQPSRS IIFASWSAGD FGSVGATEWL EGYLSSLHLK AFTYINLDKA VLGTSNFKVS ASPLLYTLIE KTMQNVKHPV TGQFLYQDSN WASKVEKLTL DNAAFPFLAYSGIPAVSFCF CEDTDYPYLG TTMDTYKELI ERIPELNKVA RAAAEVAGQF VIKLTHDVEL NLDYERYNSQ LLSFVRDLNQ YRADIKEMGL SLQWLYSARG DFFRATSRLT TDFGNAEKTD RFVMKKLNDR VMRVEYHFLS PYVSPKESPF RHVFWGSGSH TLPALLENLK LRKQNNGAFNETLFRNQLAL ATWTIQGAAN ALSGDVWDID NEFHHHHHH.
Safety Data Sheet
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.