SNRP

About SNRP / Small Nuclear Ribonucleoprotein Polypeptide:

snRNPs, otherwise known as small nuclear ribonucleoproteins, are RNA-protein complexes. They work with unmodified pre-mRNA, among other proteins, in order to create a spliceosome. This helps to create a large RNA-protein molecular complex, during which the pre-mRNA splices.

SNRP Function
snRNPs form critical functions for the removal of introns from the pre-mRNA, which is a critical component of the post-transcriptional modification of RNA. In terms of components, snRNPs are made up of RNA and protein molecules. The RNA that you’ll find within the snRNPs are small; they’re typically only around 150 nucleotides long. They were discovered by a number of scientists led by Joan A. Steitz and Michael R. Lerner. Because it was such a groundbreaking discovery, the team was awarded the 1989 Nobel Prize for Chemistry. Their research found that RNA can play a big role in cell development since they function as a catalyst.

Small Nuclear Ribonucleoprotein Polypeptide Mechanism
There are various different types of snRNPs - indeed, there are at least five -- that are involved in the splicing project. It has also been shown that antibodies may be produced that work against the body’s own snRNPs. For example, the most famous is the anti-Sm antibodies -- this targets the Sm protein, which is involved in the systemic lupus erythematosus (SLE). snRNPs have been shown to live a long time, but eventually, they begin to disassemble and downgrade. This is an area of snRNPs that is still unknown, however, because so little is known about the degradation process, at least so far.