About NFKB Inhibitor:
The NFKB alias for the protein is also NFKBI and is found in many types of animal cells. This protein complex can be categorized under a family and subfamily of proteins known as the NF-kappa-B inhibitor family.
NFKB Structure
The cell signaling has two combined proteins that have increased rates of gene expression, also known as transactivation, into the end of the C-termini amino acid chain. NFKBI is a transcription factor and unique to other transcription factors. Damaged proteins are degraded by the enzymes proteases pathway to help its selective processing. This creates the NFKB inhibitor structure, which is found in all animal cells, making it unique.
NFKB Function and Interactions
The NFKBI function of the protein cells or gene inhibits specific complexes. It signals a responsive process to cellular healing within the body due to the NFKBI being the first responder in cellular responses to negative stimulation, helping the immune system.
There are essential signaling pathways that each influence cell signaling. There are five methods or routes that are involved in NFKB signaling. This is known as the signaling molecule, the receptors, cellular activators, transcription factors and the cellular effects. They each play their roles in their interactions where the main results can include DNA transcription, cytokine production and cell survival.
NFKB Mechanism
If the receptor is inactive, it will be able to be located in the cytosol. When the signal is attached to the receptor, it activates the cell. Suppose the inhibitor is unblocked due to the signaling that begins after the proteasome’s degradation process. The different complex interactions that occur lead to the production of proteins that lead to the roles of the cell signaling pathways.