Myelin Basic Protein

About MBP / Myelin Basic Protein:

A protein called myelin essential protein (MBP) is an important building block of the myelin sheath, which provides insulation for nerve cells. It is also in peripheral nerves and other tissues.

MBP Structure
Myelin Basic Protein is a protein that has a vital role in the formation of myelin. Myelin is a substance wrapping around and insulating nerve cells, helping them conduct electrical impulses faster.

Myelin Basic Protein Gene Expression
The MBP gene is on chromosome 17 in humans and a variety of other organisms. Its protein product is myelin basic protein (MBP).

MBP Pathology
Abnormal levels of Myelin Basic Protein can be associated with neurological diseases such as Multiple Sclerosis, Guillain-Barre Syndrome, and some types of spinal cord injury.

Myelin Basic Protein Interactions
Myelin Basic Protein interacts with other molecules called proteoglycans.
Myelin is a fragile sheath that wraps around and insulates nerve cells in the central nervous system (CNS). These proteins are essential for this process because they form the bulk of this thin protective coating.
Myelin Basic Protein levels are markers for neurological diseases like Multiple Sclerosis, Guillain-Barre Syndrome, and some types of spinal cord injury.
These disorders are all characterized by damage to the CNS. Abnormal levels of Myelin Basic Protein relate to neurological diseases such as Multiple Sclerosis, Guillain-Barre Syndrome, and some types of spinal cord injury.

MBP’s Role in Disease
Myelin Basic Protein is vital for the maintenance and repair of nerve cells. When MBP levels are low, it can lead to a disease called Multiple Sclerosis (MS). MS is an autoimmune disease that attacks myelin in the central nervous system. Guillain-Barre Syndrome occurs when your immune system damages parts of your peripheral nervous system.