{"title":"Tubulin Folding Cofactor","description":"\u003ch2 class=\"highlited\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eAbout TBC \/ Tubulin Folding Cofactor:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eMicrotubules are made of two main structural components- alpha-tubulin and beta-tubulin. However, a group of cofactors is also vital for assembly component formation of the tubulin molecule in vitro. While the vitro form is just an emerging role for the cofactors, their primary biological function in vivo is unclear.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eTBC Mechanism\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eFrom a biological analysis in the mammalian system, tubulins with cofactors consist of various chaperonin subunits.\u003cbr data-mce-fragment=\"1\"\u003eTubulin folding cofactor B and A capture alpha and beta-tubulins after being released from the chaperonin complex, replacing them with cofactors E and D. the pathways converge to form a complex with four molecules. TBC is conserved from humans to yeast. For instance, budding yeast has homologs of various cofactors apart from cofactor C, which is found in mutants, genomes, and consequent genes.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eTubulin Folding Cofactor Functions\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eTubulin folding cofactors are responsible for the availability of the tubulin subunits and microtubule stability in eukaryotes. According to recent Arabidopsis mutant experiments, there is another cellular function of tubulin folding cofactors.\u003cbr data-mce-fragment=\"1\"\u003eMicrotubules have dynamic properties controlled by various microtubules-binding proteins to stabilize, cluster, depolymerize and nucleate MT. Tubulin cofactors also regulate the synthesis of tubulin subunits, the formation of dimers, and the stability of microtubules. Tubulin folding cofactors are also essential in plant development.\u003cbr data-mce-fragment=\"1\"\u003eInitially, tubulin folding cofactor activity was discovered through vertebrate proteins. Recent studies have shown that tubulin folding cofactors are vital in plant morphogenesis. However, there is no evidence to show their role in multicellular development.\u003c\/p\u003e","products":[{"product_id":"tbca-human","title":"TBCA Human","description":"\u003cp\u003eTubulin Folding Cofactor A Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTubulin-specific chaperone A, Tubulin-folding cofactor A, CFA, TCP1-chaperonin cofactor A, TBCA.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174569279572,"sku":"PRO-705","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25µg","offer_id":43174569312340,"sku":"PRO-705","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174569345108,"sku":"PRO-705","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-tbca-human-PRO-705.png?v=1776711659"},{"product_id":"tbcb-human","title":"TBCB Human","description":"\u003cp\u003eTubulin Folding Cofactor B Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTubulin folding cofactor B, Cytoskeleton-associated protein CKAPI, cytoskeleton associated protein 1, CKAP1, CG22, Tubulin-specific chaperone B.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174571343956,"sku":"PRO-1127","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25µg","offer_id":43174571376724,"sku":"PRO-1127","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174571409492,"sku":"PRO-1127","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-tbcb-human-PRO-1127.png?v=1776711667"},{"product_id":"tbcc-human","title":"TBCC Human","description":"\u003cp\u003eTubulin Folding Cofactor C Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTubulin folding cofactor C, tubulin-specific chaperone c, Tubulin-folding cofactor C, CFC.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174572228692,"sku":"PRO-1180","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174572261460,"sku":"PRO-1180","price":145.0,"currency_code":"USD","in_stock":true},{"title":"100µg","offer_id":43174572294228,"sku":"PRO-1180","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-tbcc-human-PRO-1180.png?v=1776711672"},{"product_id":"tbcel-human","title":"TBCEL Human","description":"\u003cp\u003eTubulin Folding Cofactor E-Like Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTubulin Folding Cofactor E-Like, E-Like, LRRC351, Leucine Rich Repeat Containing Catastrophin, Tubulin-Specific Chaperone E-Like.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174574260308,"sku":"PRO-030","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174574293076,"sku":"PRO-030","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174574325844,"sku":"PRO-030","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-tbcel-human-PRO-030.png?v=1776711680"},{"product_id":"tppp3-human","title":"TPPP3 Human","description":"\u003cp\u003eTubulin Polymerization-Promoting Protein Family Member 3 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTubulin Polymerization-Promoting Protein Family Member 3, Brain Specific Protein, p25gamma, TPPP\/p20, p20.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174856196180,"sku":"PRO-1615","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174856228948,"sku":"PRO-1615","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174856261716,"sku":"PRO-1615","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-tppp3-human-PRO-1615.png?v=1776713103"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/collections\/Image_c1d6fad0-2498-4e17-a003-f41ebbb610fd.png?v=1700648022","url":"https:\/\/prospecbio.com\/collections\/tubulin-folding-cofactor.oembed","provider":"prospecbio","version":"1.0","type":"link"}