{"title":"TTC","description":"\u003ch2 class=\"highlited\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eAbout TTC \/ Tetratricopeptide Repeat Domain:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eTTC, also known as Tetratricopetide repeat proteins, is a series of proteins that are encoded by the TTC1, TTC3, TTC4, TTC5, TTC6, TTC7A, TTC7B, TTC8, TTC9C, TTC12, TTC13, TTC14, TTC15, TTC16, TTC17, TTC18, TTC21A, TTC21B, TTC22, TTC24, TTC25, TTC27, TTC28, TTC29, TTC30A, TTC30B, TTC31, TTC33, and TTC37 genes. They are examples of genes that feature the tetratricopeptide repeat structure motif.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eTTC Function\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eHow TTC proteins function remains, by and large, unclear. Some of them play a role in Cilia formation and function, with many of them showing roles in protein complex formation. Nine of them are known as components of IFT or BBSome complexes.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eTetratricopeptide Repeat Domain Mechanism\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eThe specifics of the exact molecular mechanism of the TTC proteins are unknown, and they are each likely to have their own mechanisms.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eTTC Interactions\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eThere are various interactions between the TTC proteins and other genes. TTC1 is known to interact with TRIP6 (Thyroid Hormone Receptor Interactor 6), TTLL12 (Tubulin Tyrosine Ligase Like 12), ZRANB2 (Zinc Finger RANBP2-Type Containing 2), UBE2B (Ubiquitin Conjugating Enzyme E2 B), and SSSCA1 (Zinc Ribbon Domain Containing 2).\u003cbr data-mce-fragment=\"1\"\u003eTTC3 interacts with UBE2D2 (Ubiquitin Conjugating Enzyme E2 D2), UBC (Ubiquitin C), AKT1 (AKT Serine\/Threonine Kinase 1), AKT3 (AKT Serine\/Threonine Kinase 2), and DYNC2LI1 (Dynein Cytoplasmic 2 Light Intermediate Chain 1).\u003cbr data-mce-fragment=\"1\"\u003eThere are several more TTC proteins, each with its own interactions.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eTetratricopeptide Repeat Domain Structure\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eThe structures of the various TTC genes differ, but a typical structure is characterized by interactions between helices A and B of the first motif and helix A’ of the next TPR.\u003c\/p\u003e","products":[{"product_id":"ttc1-human","title":"TTC1 Human","description":"\u003cp\u003eTetratricopeptide Repeat Domain 1 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTetratricopeptide repeat protein 1, TPR repeat protein 1, TTC1, TPR1.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174946177108,"sku":"PRO-1160","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174946209876,"sku":"PRO-1160","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174946242644,"sku":"PRO-1160","price":3600.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-ttc1-human-PRO-1160.png?v=1776713550"},{"product_id":"ttc32-human","title":"TTC32 Human","description":"\u003cp\u003eTetratricopeptide Repeat Domain 32 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTetratricopeptide Repeat Domain 32, Tetratricopeptide Repeat Protein 32, TPR Repeat Protein 32.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174947127380,"sku":"PRO-1246","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174947160148,"sku":"PRO-1246","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174947192916,"sku":"PRO-1246","price":3600.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-ttc32-human-PRO-1246.png?v=1776713555"},{"product_id":"ttc33-human","title":"TTC33 Human","description":"\u003cp\u003eTetratricopeptide Repeat Domain 33 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTetratricopeptide Repeat Domain 33, Osmosis-Responsive Factor, Tetratricopeptide Repeat Protein 33, TPR Repeat Protein 33, OSRF.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174947913812,"sku":"PRO-1217","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174947946580,"sku":"PRO-1217","price":145.0,"currency_code":"USD","in_stock":true},{"title":"100µg","offer_id":43174947979348,"sku":"PRO-1217","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-ttc33-human-PRO-1217.png?v=1776713561"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/collections\/Image_babec7ff-f292-4734-ab1b-d27aca373f62.png?v=1700648064","url":"https:\/\/prospecbio.com\/collections\/ttc.oembed","provider":"prospecbio","version":"1.0","type":"link"}