{"title":"Tropomyosin","description":"\u003ch2 class=\"highlited\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eAbout TPM \/ Tropomyosin:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eTropomyosin (TPM) is a two-stranded, coiled coil, alpha-helical protein, which can be found in actin-based cytoskeletons.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eTPM Function\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eAll organisms have organelles that ensure cells have physical integrity. Collectively, these kinds of organelles are known as the cytoskeleton. This is one of the oldest systems that focuses on the protein actin’s filamentous polymers.\u003cbr data-mce-fragment=\"1\"\u003eTropomyosin, which is a polymer of a second protein, is imperative in most actin filaments found within animals.\u003cbr data-mce-fragment=\"1\"\u003eTropomyosin represents a big family of integral components of actin filaments, which play a chief role when it comes to the regulation of the function of actin filaments, in both non-muscle and muscle cells.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eTropomyosin Structure\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eThese proteins feature a homo-dimer or a coiled coil, rod-shaped hetero-dimer, which lies along the a-helical groove in the majority of actin filaments.\u003cbr data-mce-fragment=\"1\"\u003eThe length of the actin filament is where the interaction takes place, with the dimers being aligned in a head-to-tail manner.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eTPM Types\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eThere are two groups which tropomyosins tend to be categorized into; non-muscle tropomyosin isoforms and muscle tropomyosin isoforms.\u003cbr data-mce-fragment=\"1\"\u003eMuscle tropomyosin isoforms are part of the regulation of the interactions between myosin and actin in the muscle sarcomere. They play a chief role when it comes to muscle contraction regulation.\u003cbr data-mce-fragment=\"1\"\u003eOn the other hand, non-muscle tropomyosin isoforms function in all cells, including both non-muscle and muscle cells. They play a part in a wide range of cellular pathways, helping in terms of controlling and regulating the cytoskeleton of the cell, as well as a number of other significant cellular functions.\u003c\/p\u003e","products":[{"product_id":"tpm1-human","title":"TPM1 Human","description":"\u003cp\u003eTropomyosin-1 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTropomyosin alpha-1 chain, Tropomyosin-1, Alpha-tropomyosin, TPM1, C15orf13, TMSA, CMD1Y, HTM-alpha.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174844661844,"sku":"PRO-469","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174844694612,"sku":"PRO-469","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174844727380,"sku":"PRO-469","price":4800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-tpm1-human-PRO-469.png?v=1776713067"},{"product_id":"tpm2-human","title":"TPM2 Human","description":"\u003cp\u003eTropomyosin-2 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTropomyosin 2 (beta), DA1, TMSB, DA2B, AMCD1, NEM4, Arthrogryposis Multiplex Congenital Distal-Type 1, beta-Tropomyosin.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"1µg","offer_id":43174845546580,"sku":"PRO-069","price":60.0,"currency_code":"USD","in_stock":true},{"title":"5µg","offer_id":43174845579348,"sku":"PRO-069","price":145.0,"currency_code":"USD","in_stock":true},{"title":"50µg","offer_id":43174845612116,"sku":"PRO-069","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-tpm2-human-PRO-069.png?v=1776713070"},{"product_id":"tpm3-human","title":"TPM3 Human","description":"\u003cp\u003eTropomyosin-3 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTropomyosin alpha-3 chain, Gamma-tropomyosin, Tropomyosin-3, Tropomyosin-5, hTM5, TPM3, TM3, TM5, TRK, CFTD, NEM1, TM-5, TM30, TM30nm, TPMsk3, hscp30, OK\/SW-cl.5.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174846398548,"sku":"PRO-1020","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174846431316,"sku":"PRO-1020","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174846464084,"sku":"PRO-1020","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-tpm3-human-PRO-1020.png?v=1776713075"},{"product_id":"tpm4-human","title":"TPM4 Human","description":"\u003cp\u003eTropomyosin-4 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTropomyosin alpha-4 chain, TM30p1, Tropomyosin-4, TPM4.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174847381588,"sku":"PRO-187","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174847414356,"sku":"PRO-187","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174847447124,"sku":"PRO-187","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-tpm4-human-PRO-187.png?v=1776713080"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/collections\/Image_23bbdb28-e61e-403f-913a-13ce733324b8.png?v=1700648051","url":"https:\/\/prospecbio.com\/collections\/tropomyosin.oembed","provider":"prospecbio","version":"1.0","type":"link"}