{"title":"Transcription Elongation Factor","description":"\u003ch2 class=\"highlited\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eAbout Transcription Elongation Factor:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eElongation factors are a set of proteins functioning at the ribosome, throughout the process of protein synthesis, that help translational elongational f the first to the last peptide bond of a growing polypeptide. The transcription elongation factors include Transcription Elongation Factor A1 (TCEA1), Transcription Elongation Factor A3 (TCEA2), and Transcription Elongation Factor A3 (TCEA3)\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eTranscription Elongation Factor Function\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eTCEA1 primarily helps to resolve backtracked elongation complexes by making a cut in the RNAP active site and is also present in the eukaryotic transcription preinitiation complex. TCEA2 is found in the nucleus and releases RNA polymerase II ternary complexes from transcriptional arrest at template-encoded arresting sites. TCEA3 promotes muscle-specific gene expression during myogenesis\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eTranscription Elongation Factor Interactions\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eTCEA1 interacts with POLR2A (RNA Polymerase II, I And III Subunit A), POLR2E (RNA Polymerase II, I And III Subunit E), POLR2F (RNA Polymerase II, I And III Subunit F), GTF2F2 (General Transcription Factor IIF Subunit 2), and GTF2B (General Transcription Factor IIB).\u003cbr data-mce-fragment=\"1\"\u003eTCEA2 interacts with POLR2F, POLR2H (RNA Polymerase II, I And III Subunit H), POLR2I (RNA Polymerase II, I And III Subunit I), POLR2K (RNA Polymerase II, I And III Subunit K) and GTF2B.\u003cbr data-mce-fragment=\"1\"\u003eTCEA3 interacts with POLR2F, POLR2H, POLR2I, POLR2K, and POLR2L (RNA Polymerase II, I And III Subunit L).\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eTranscription Elongation Factor Structure\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eTCEA1 has a size of 301 amino acids and a molecular mass of 33970 DA, and a quaternary structure that interacts with EAF2 and associates with UBR5 and formats a transcription regulatory complex made of CDK9, RNAP II, UBR5, and TFIIS\/TCEA1 that can stimulate target gene transcription (e.g., gamma fibrinogen\/FGG) by recruiting their promoters.\u003c\/p\u003e","products":[{"product_id":"tceb2-human","title":"ELOB Human","description":"\u003cp\u003eElongin-B Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eELOB, SIII, Elongin B, Transcription elongation factor B polypeptide 2, RNA polymerase II transcription factor SIII subunit B, SIII p18, Elongin 18 kDa subunit, TCEB2.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"10µg","offer_id":43174367428692,"sku":"PRO-664","price":60.0,"currency_code":"USD","in_stock":true},{"title":"50µg","offer_id":43174367461460,"sku":"PRO-664","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174367494228,"sku":"PRO-664","price":1800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-tceb2-human-PRO-664.png?v=1776711771"},{"product_id":"elongin-b-human","title":"ELOB Mouse","description":"\u003cp\u003eElongin B Mouse Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTranscription elongation factor B polypeptide 2, TCEB2, RNA polymerase IItranscription factor SIII subunit B, SIII p18, EloB, Elongin 18 kDa subunit.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174368411732,"sku":"PRO-2550","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174368444500,"sku":"PRO-2550","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174368477268,"sku":"PRO-2550","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-elongin-b-human-PRO-2550.png?v=1776683628"},{"product_id":"tcea1-human","title":"TCEA1 Human","description":"\u003cp\u003eTranscription Elongation Factor A (SII)-1 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTranscription elongation factor A (SII) 1, Transcription elongation factor TFIIS.o, TCEA, GTF2S, SII, TF2S.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174583337044,"sku":"PRO-1098","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174583369812,"sku":"PRO-1098","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174583402580,"sku":"PRO-1098","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-tcea1-human-PRO-1098.png?v=1776711727"},{"product_id":"tcea2-human","title":"TCEA2 Human","description":"\u003cp\u003eTranscription Elongation Factor A (SII)-2 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTranscription elongation factor A protein 2, Testis-specific S-II, Transcription elongation factor S-II protein 2, Transcription elongation factor TFIIS.l, TCEA2, TFIIS, Transcription Elongation Factor A (SII) 2.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174584320084,"sku":"PRO-1489","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174584352852,"sku":"PRO-1489","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174584385620,"sku":"PRO-1489","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-tcea2-human-PRO-1489.png?v=1776711732"},{"product_id":"tceal1-human","title":"TCEAL1 Human","description":"\u003cp\u003eTranscription Elongation Factor A (SII)-Like 1 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTranscription elongation factor A protein-like 1, TCEA-like protein 1, Nuclear phosphoprotein p21\/SIIR, Transcription elongation factor S-II protein-like 1, TCEAL1, SIIR, p21, pp21.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174585237588,"sku":"PRO-507","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174585270356,"sku":"PRO-507","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174585303124,"sku":"PRO-507","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-tceal1-human-PRO-507.png?v=1776711750"},{"product_id":"tceal3-human","title":"TCEAL3 Human","description":"\u003cp\u003eTranscription Elongation Factor A (SII)-Like 3 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTranscription elongation factor A (SII)-like 3, TCEA-like protein 3, MGC15737.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174586122324,"sku":"PRO-1128","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174586155092,"sku":"PRO-1128","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174586187860,"sku":"PRO-1128","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-tceal3-human-PRO-1128.png?v=1776711754"},{"product_id":"tceal7-human","title":"TCEAL7 Human","description":"\u003cp\u003eTranscription Elongation Factor A (SII)-Like 7 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTranscription elongation factor A (SII)-like 7, TCEA-like protein 7, transcription elongation factor A protein-like 7, MGC23947, MPMGp800C04260Q003.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174587400276,"sku":"PRO-1147","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174587433044,"sku":"PRO-1147","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174587465812,"sku":"PRO-1147","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-tceal7-human-PRO-1147.png?v=1776711758"},{"product_id":"tceal8-human","title":"TCEAL8 Human","description":"\u003cp\u003eTranscription Elongation Factor A (SII)-Like 8 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTranscription elongation factor A protein-like 8, TCEA-like protein 8, Transcription elongation factor S-II protein-like 8, TCEAL8.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174588252244,"sku":"PRO-1188","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174588285012,"sku":"PRO-1188","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174588317780,"sku":"PRO-1188","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-tceal8-human-PRO-1188.png?v=1776711763"},{"product_id":"tceb1-human","title":"TCEB1 Human","description":"\u003cp\u003eTranscription Elongation Factor B Polypeptide 1 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTranscription elongation factor B polypeptide 1, Elongin 15 kDa subunit, Elongin-C, EloC, RNA polymerase II transcription factor SIII subunit C, SIII p15, TCEB1, SIII.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174588973140,"sku":"PRO-1017","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174589005908,"sku":"PRO-1017","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174589038676,"sku":"PRO-1017","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-tceb1-human-PRO-1017.png?v=1776711767"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/collections\/Image_1dfe5f42-d148-4d9f-b1f3-530e1493951a.png?v=1700646672","url":"https:\/\/prospecbio.com\/collections\/transcription-elongation-factor.oembed","provider":"prospecbio","version":"1.0","type":"link"}