{"title":"Trafficking Protein Particle Complex","description":"\u003ch2 class=\"highlited\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eAbout TRAPPC \/ Trafficking Protein Particle Complex:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eThe TRAPP complex, or the Transport Protein Particle, is a protein that is essential in the transport of particles between organelles. There are two forms of this complex, TRAPP I and TRAPP II. TRAPP I is a multisubunit complex that consists of seven subunits (Bet5, Bet3, Trs20, Trs23, Trs31, Trs33, Trs85) while TRAPP II has three additional subunits (Trs65, Trs120, and Trs130).\u003cbr data-mce-fragment=\"1\"\u003eThe subunits named above have the name of TRAPP complex particles in yeast, but they are also genes in mammals. These are called TRAPPC1, TRAPPC2, TRAPPC2L, TRAPPC3, TRAPPC3L, TRAPPC4, TRAPPC5, TRAPPC6A, TRAPPC6B, TRAPPC8, TRAPPC9, TRAPPC10, TRAPPC11, TRAPPC13, and TRAPPC14.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eTRAPPC Function\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eTRAPP complexes are transported protein particles that play a role in endoplasmic reticulum-to-Golgi transport and also acts as a Ypt\/Rab GTPase nucleotide exchanger, GEF. These are the functions that have been identified in yeast, but the role that the two TRAPP complexes present in humans play is less clear.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eTrafficking Protein Particle Complex Mechanism\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eThe mechanisms for the TRAPP Complex parties are still uncertain. Some mechanisms in yeast TRAPP complexes have been identified, but in mammals, it is through the TRAPP could act as a membrane tether.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eTRAPPC Interactions\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eEach TRAPP complex gene has its own interactions. For instance, Bet5, also known as the TRAPPC1 Gene, interacts with TRAPPC2, TRAPPC3, TRAPPC4, TRAPPC5, and TRAPPC9 genes. Trs20, also known as TRAPPC2, interacts with TRAPPC1, TRAPPC3, TRAPPC5, TRAPPC6A, and TRACC6B\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eTrafficking Protein Particle Complex Structure\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eStructurally, TRAPP subunits fall into two groups. The first group, which includes Trs20 and Trs23 has a longin-domain fold involved in protein-protein interactions. The second group, which includes Trs31 and Trs33, have similar structures.\u003c\/p\u003e","products":[{"product_id":"trappc2-human","title":"TRAPPC2 Human","description":"\u003cp\u003eTrafficking Protein Particle Complex 2 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTrafficking Protein Particle Complex 2, Sedlin, SEDL, Trafficking Protein Particle Complex Subunit 2, Spondyloepiphyseal Dysplasia Late, TRAPPC2P1, HYP38334, ZNF547L, MIP2A, TRS20, SEDT, TRAPPC2.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174873923668,"sku":"PRO-1272","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174873956436,"sku":"PRO-1272","price":145.0,"currency_code":"USD","in_stock":true},{"title":"100µg","offer_id":43174873989204,"sku":"PRO-1272","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-trappc2-human-PRO-1272.png?v=1776713196"},{"product_id":"trappc2l-human","title":"TRAPPC2L Human","description":"\u003cp\u003eTrafficking Protein Particle Complex 2-Like Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTrafficking protein particle complex subunit 2-like protein, TRAPPC2L.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174875005012,"sku":"PRO-1543","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174875037780,"sku":"PRO-1543","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174875070548,"sku":"PRO-1543","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-trappc2l-human-PRO-1543.png?v=1776713201"},{"product_id":"trappc3-human","title":"TRAPPC3 Human","description":"\u003cp\u003eTrafficking Protein Particle Complex 3 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTrafficking protein particle complex subunit 3, BET3, BET3 homolog, 1110058K12Rik.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174876119124,"sku":"PRO-1056","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174876151892,"sku":"PRO-1056","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174876184660,"sku":"PRO-1056","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-trappc3-human-PRO-1056.png?v=1776713206"},{"product_id":"trappc4-human","title":"TRAPPC4 Human","description":"\u003cp\u003eTrafficking Protein Particle Complex 4 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTrafficking protein particle complex subunit 4, TRS23\nhomolog, Synbindin, Hematopoietic stem\/progenitor cell protein 172.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174877003860,"sku":"PRO-1273","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174877036628,"sku":"PRO-1273","price":145.0,"currency_code":"USD","in_stock":true},{"title":"100µg","offer_id":43174877069396,"sku":"PRO-1273","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-trappc4-human-PRO-1273.png?v=1776713211"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/collections\/Image_8e9e8f48-3cd0-4698-ad2d-1c746f7a8e97.png?v=1700648053","url":"https:\/\/prospecbio.com\/collections\/trafficking-protein-particle-complex.oembed","provider":"prospecbio","version":"1.0","type":"link"}