{"title":"STIP","description":"\u003ch2 class=\"highlited\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eAbout STIP1 \/ Stress-Induced-Phosphoprotein 1:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003ePhosphoprotein stress-inducible protein (STIP11) is a less well-characterized member of the STING family that was recently discovered. Phosphoprotein is not induced by general cellular stresses, but it responds to specific conditions such as oxidative DNA damage, and DNA replication blockade.\u003cbr data-mce-fragment=\"1\"\u003eStress-induced-phosphoprotein (STIP1) is a protein that takes part in the activation of the mammalian digestive system. It is involved in signaling and its effectiveness has been found to be dependent on the cellular composition of the gut.\u003cbr data-mce-fragment=\"1\"\u003eThe existence of STIP11 is vital to our ability to digest and absorb food and survive.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eSTIP1 Interactions\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eSome studies have indicated that phosphoprotein STIP1 interacts with cAMP receptor protein\/cAMP response element-binding protein (CREB) signaling pathway in mammalian cells. It may be involved in protection against oxidative DNA damages. In addition, some studies have suggested that this protein may also play a role in the sensitization of cells to chemotherapeutic agents.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eStress-Induced-Phosphoprotein 1 Expression\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eThis protein has been found in the different tissues and organs of the body, such as skeletal muscle and kidneys. Furthermore, phosphoprotein STIP1 is also reported to be expressed on cells of various cancers including primary tumors of the breast, lung, pancreas, ovary, and colon tumor as well as those in triple-negative breast cancer (TNBC). The level of phosphoprotein STIP1 is also elevated in metastatic leiomyosarcoma cells.\u003c\/p\u003e","products":[{"product_id":"human-stip1","title":"STIP1 Human","description":"\u003cp\u003eStress-Induced-Phosphoprotein 1 Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eStress Induced Phosphoprotein 1, Transformation-Sensitive\nProtein IEF SSP 3521, Renal Carcinoma Antigen NY-REN-11,\nStress-Induced-Phosphoprotein 1, Hsp70\/Hsp90-Organizing Protein,\nHsc70\/Hsp90-Organizing Protein, STI1, HOP, Epididymis Secretory Sperm Binding\nProtein Li 94n, NY-REN-11 Antigen, IEF-SSP-3521, HEL-S-94n, STI1L, P60.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174432309332,"sku":"PRO-2334","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25µg","offer_id":43174432342100,"sku":"PRO-2334","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174432374868,"sku":"PRO-2334","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-human-stip1-PRO-2334.png?v=1776697683"},{"product_id":"stip1-human","title":"STIP1 Human, His","description":"\u003cp\u003eStress-Induced-Phosphoprotein 1 Human Recombinant, His Tag\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eHOP, P60, STI1, STI1L, IEF-SSP-3521, STIP1, Stress-induced-phosphoprotein 1, Hsc70\/Hsp90-organizing protein, Transformation-sensitive protein IEF SSP 3521, Renal carcinoma antigen NY-REN-11.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174433292372,"sku":"PRO-753","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174433325140,"sku":"PRO-753","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174433357908,"sku":"PRO-753","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-stip1-human-PRO-753.png?v=1776711126"},{"product_id":"stip1-mouse","title":"STIP1 Mouse","description":"\u003cp\u003eStress-Induced-Phosphoprotein 1 Mouse Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eHop, p60, Sti1, STI1, mSTI1, Stress-induced-phosphoprotein\n1, Hsc70\/Hsp90-organizing protein.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174434472020,"sku":"PRO-2396","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174434504788,"sku":"PRO-2396","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174434537556,"sku":"PRO-2396","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-stip1-mouse-PRO-2396.png?v=1776711131"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/collections\/Image_409829bf-f9d7-4ba3-aa76-e908321fbd82.png?v=1700647997","url":"https:\/\/prospecbio.com\/collections\/stip.oembed","provider":"prospecbio","version":"1.0","type":"link"}