{"title":"Signal Sequence Receptor","description":"\u003ch2 class=\"highlited\" data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eAbout SSR \/ Signal Sequence Receptor:\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eSSR is a signal sequence receptor protein that belongs to the serine\/threonine kinases signal transduction pathway. It can be found in the cytosol of the eukaryotic cell, stabilized by a signal peptide that serves as an import signal for protein translocation into wall-less organelles.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eSSR Protein Structure\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eWithin cells, the SSR structure has a small cytoplasmic N Terminal signal sequence followed by four homologous domains (D1–D4), with each domain consisting of two-stranded antiparallel beta-sheets surrounded by eight alpha-helices. The C­ Terminal portion contains a short helical hairpin and five leucines residues; which are involved in dimerization of the SSR protein.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eSignal Sequence Receptor Interactions\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eThere are some signal sequence receptor partner proteins, such as signal sequence binding protein 1(SSBP1), signal peptide peptidase (SPP), signal peptide factor 2 (SPF2) and signal recognition particle (SRP). The signal sequence receptor holds a central part in regulating intracellular transport and targeting signals. SSR signal sequence receptor protein-binding proteins can regulate signal blockade and signal recognition.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eSSR Function\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eSignal sequence receptor is one of the key elements in the signal transduction pathway. Signal sequence receptor plays a role in targeting the signal peptide to certain organelles. To recognize and distinguish between intracellular transport signals, signal receptors are needed since intracellular transport sequencer (IDS) or signal peptide transporter (SPT) can't recognize all types of intracellular transport signals\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eSignal Sequence Receptor Cellular Location\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eThe cytosol of the eukaryotic cell, stabilized by a signal peptide that serves as an import signal for protein translocation into wall-less organelles. signal sequence receptors are composed of a signal peptide, signal recognition particle (SRP), signal sequence binding protein 1(SSBP1) and signal sequence receptor.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eSSR Pathway\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003eIn the signal pathway, signal receptors bind to substrates with specific intracellular transport signals and control the direction of divergent transport. Signal proteins have a transit peptide at their N terminus that directs them into organelles while targeting proteins typically lack a signal segment. Proteins destined for the nucleus are directed there through interaction with the nuclear localization signal (NLS) in many cases.\u003c\/p\u003e","products":[{"product_id":"ssr1-human","title":"SSR1 Human","description":"\u003cp\u003eSignal Sequence Receptor, Alpha Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eSignal Sequence Receptor Alpha, Translocon-Associated\nProtein Alpha, SSR Alpha Subunit, TRAP-alpha, TRAPA.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"2µg","offer_id":43174396887124,"sku":"PRO-1772","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10µg","offer_id":43174396919892,"sku":"PRO-1772","price":145.0,"currency_code":"USD","in_stock":true},{"title":"100µg","offer_id":43174396952660,"sku":"PRO-1772","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-ssr1-human-PRO-1772.png?v=1776710964"},{"product_id":"ssr2-human","title":"SSR2 Human","description":"\u003cp\u003eSignal Sequence Receptor, Beta Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eHSD25, TLAP, TRAP-BETA, TRAPB, Translocon-associated protein subunit beta, Signal sequence receptor subunit beta, SSR-beta.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174399148116,"sku":"PRO-1380","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174399180884,"sku":"PRO-1380","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174399213652,"sku":"PRO-1380","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-ssr2-human-PRO-1380.png?v=1776710974"},{"product_id":"ssr4-human","title":"SSR4 Human","description":"\u003cp\u003eSignal Sequence Receptor, Delta Human Recombinant\u003c\/p\u003e\n\n\u003cdiv class=\"synonyms_hide\"\u003e\n  \u003cp\u003eTRAPD, Translocon-associated protein subunit delta, TRAP-delta, Signal sequence receptor subunit delta SSR-delta.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"prospecbio","offers":[{"title":"5µg","offer_id":43174400786516,"sku":"PRO-1294","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20µg","offer_id":43174400819284,"sku":"PRO-1294","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1mg","offer_id":43174400852052,"sku":"PRO-1294","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/files\/Prospecbio-ssr4-human-PRO-1294.png?v=1776710983"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0559\/3219\/0804\/collections\/Image_926d3a4d-be63-4d4c-9f88-8b8465683f02.png?v=1700647915","url":"https:\/\/prospecbio.com\/collections\/signal-sequence-receptor.oembed","provider":"prospecbio","version":"1.0","type":"link"}